...BRCA2 region. Five families showed strong evidence of linkage. The maximum two-point LOD scores for the five BRCA2-linke...
...BRCA2, which is responsible for the increased incidence of breast cancer in Kindred 107.
...BRCA2 lend urgency to the need to assess breast cancer intervention and prevention strategies for women likely to carry ...
The purpose of this investigation was to determine if there are pathobiologic differences between BRCA1-related and BRCA...
...BRCA2 locus has been observed in 30-40% of sporadic breast and ovarian tumours, implying that BRCA2 may act as a tumour ...
...BRCA2 (refs 5-8), accounts for a proportion of breast cancer roughly equal to BRCA1. Like BRCA1, BRCA2 behaves as a domi...
...BRCA2 (ref. 2), TP53 (ref. 3) or ataxia telangiectasia (ATM) genes, each of which is considered to be a tumour suppresso...
...BRCA2 gene, which maps to the long arm of chromosome 13 by linkage analysis. Mutations in BRCA2 account for approximatel...
...BRCA2 locus. The final assembly consists of a yeast artificial chromosome (YAC) contig with 42 members spanning the 13q1...
...BRCA2 also includes a motif similar to the granin consensus at the C terminus of the protein. Both BRCA1 and the granins...
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