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Frequent occurrence of BRCA2 linkage in Icelandic breast cancer families and ...

Gudmundsson(J),Johannesdottir(G),Arason(A)... Am J Hum Genet 1996-07-18

...BRCA2 region. Five families showed strong evidence of linkage. The maximum two-point LOD scores for the five BRCA2-linke...

A 45-year follow-up of kindred 107 and the search for BRCA2.

Goldgar(D E),Neuhausen(S L),Steele(L),Fiel... J Natl Cancer Inst Monogr 1996-03-13

...BRCA2, which is responsible for the increased incidence of breast cancer in Kindred 107.

Developing strategies for intervention and prevention in hereditary breast ca...

Weber(B L),Giusti(R M),Liu(E T) J Natl Cancer Inst Monogr 1996-03-13

...BRCA2 lend urgency to the need to assess breast cancer intervention and prevention strategies for women likely to carry ...

Hereditary breast cancer: pathobiology, prognosis, and BRCA1 and BRCA2 gene l...

Marcus(J N),Watson(P),Page(D L),Narod(S A)... Cancer 1996-06-07

The purpose of this investigation was to determine if there are pathobiologic differences between BRCA1-related and BRCA...

BRCA2 mutations in primary breast and ovarian cancers.

Lancaster(J M),Wooster(R),Mangion(J),Phela... Nat Genet 1996-07-16

...BRCA2 locus has been observed in 30-40% of sporadic breast and ovarian tumours, implying that BRCA2 may act as a tumour ...

Low incidence of BRCA2 mutations in breast carcinoma and other cancers.

Teng(D H),Bogden(R),Mitchell(J),Baumgard(M... Nat Genet 1996-07-16

...BRCA2 (refs 5-8), accounts for a proportion of breast cancer roughly equal to BRCA1. Like BRCA1, BRCA2 behaves as a domi...

Mutation analysis in the BRCA2 gene in primary breast cancers.

Miki(Y),Katagiri(T),Kasumi(F),Yoshimoto(T)... Nat Genet 1996-07-16

...BRCA2 (ref. 2), TP53 (ref. 3) or ataxia telangiectasia (ATM) genes, each of which is considered to be a tumour suppresso...

Inherited breast cancer.

Radford(D M),Zehnbauer(B A) Surg Clin North Am 1996-05-28

...BRCA2 gene, which maps to the long arm of chromosome 13 by linkage analysis. Mutations in BRCA2 account for approximatel...

A high-resolution annotated physical map of the human chromosome 13q12-13 reg...

Fischer(S G),Cayanis(E),de Fatima Bonaldo(... Proc Natl Acad Sci U S A 1996-03-01

...BRCA2 locus. The final assembly consists of a yeast artificial chromosome (YAC) contig with 42 members spanning the 13q1...

BRCA1 is secreted and exhibits properties of a granin.

Jensen(R A),Thompson(M E),Jetton(T L),Szab... Nat Genet 1996-03-25

...BRCA2 also includes a motif similar to the granin consensus at the C terminus of the protein. Both BRCA1 and the granins...

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