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Two distinct commonly deleted regions on chromosome 13q suggest involvement o...

Tsukamoto(K),Ito(N),Yoshimoto(M),Iwase(T),... Cancer 1996-12-05

...BRCA2, and the retinoblastoma susceptibility gene (RB) on the same chromosomal arm implies that one or the other, or bot...

Brca2 is coordinately regulated with Brca1 during proliferation and different...

Rajan(J V),Wang(M),Marquis(S T),Chodosh(L ... Proc Natl Acad Sci U S A 1996-12-30

...Brca2, in mammary epithelial cells as a function of proliferation and differentiation. Our results demonstrate that Brca...

German family study on hereditary breast-ovarian cancer.

Hamann(U),Becher(H),Zimmermann(T),Pella(K)... J Med Genet 1996-12-27

...BRCA2. Positive lod scores at BRCA2 were obtained in six families.

Identification and characterization of three genes and two pseudogenes on chr...

de Fatima Bonaldo(M),Jelenc(P),Su(L),Lawto... Hum Genet 1996-12-03

...BRCA2 gene on chromosome 13. All genes and pseudogenes were localized to cytogenetic bands by in situ hybridization of m...

Loss of heterozygosity studies at the retinoblastoma and breast cancer suscep...

Pearce(S H),Trump(D),Wooding(C),Sheppard(M... Clin Endocrinol (Oxf) 1996-12-18

...BRCA2 locus, suggests that tumour suppressor genes in this region other than Rb or BRCA2 may be involved in the developm...

Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2.

Roa(B B),Boyd(A A),Volcik(K),Richards(C S) Nat Genet 1996-11-12

BRCA1 and BRCA2 are the two major identified causes of inherited breast cancer, with mutations in either gene conferring...

The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish i...

Oddoux(C),Struewing(J P),Clayton(C M),Neuh... Nat Genet 1996-11-12

Certain germline mutations in either BRCA1 or BRCA2 confer a lifetime risk of developing breast cancer that may approach...

Mutations in the BRCA2 gene in hepatocellular carcinomas.

Katagiri(T),Nakamura(Y),Miki(Y) Cancer Res 1996-11-04

...BRCA2 expression in adult liver tissue, the evidence implies that inactivation of BRCA2 may play some role in developmen...

Cell cycle control of BRCA2.

Vaughn(J P),Cirisano(F D),Huper(G),Berchuc... Cancer Res 1996-11-04

...BRCA2 gene expression may implicate roles for the function of the tumor suppressor gene. In this study, expression of BR...

A large multisite cancer family is linked to BRCA2.

Tonin(P),Ghadirian(P),Phelan(C),Lenoir(G M... J Med Genet 1996-12-05

...BRCA2 gene locus (lod = 3.67 at D13S289). A number of cancers of other types occurred in this family, including three ca...

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