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A common mutation in BRCA2 that predisposes to a variety of cancers is found ...

Berman(D B),Costalas(J),Schultz(D C),Grana... Cancer Res 1996-09-30

Recent studies have identified mutations in the breast and (ovarian cancer susceptibility gene 2 (BRCA2), one which has ...

Epidemiology and prevention of breast cancer.

Kelsey(J L),Bernstein(L) Annu Rev Public Health 1996-10-04

...BRCA2 genes are associated with an inherited susceptibility to breast cancer at an early age. Other markers of increased...

Validation of family history of breast cancer and identification of the BRCA1...

Anton-Culver(H),Kurosaki(T),Taylor(T H),Gi... Genet Epidemiol 1996-11-12

...BRCA2 there were five (1.4%) probands, three below age 50 years and two 50 years or older. Site-specific familial breast...

[Genetic alterations and DNA-based diagnosis in breast cancer].

Matsumoto(S),Emi(M),Kasumi(F),Nakamura(Y) Nihon Geka Gakkai Zasshi 1996-09-10

...BRCA2. We performed PCR-SSCP analysis to determine the role of the BRCA1 gene in Japanese breast cancer and investigated...

A novel p53 germline alteration identified in a late onset breast cancer kind...

Sun(X F),Johannsson(O),Håkansson(S),Sellbe... Oncogene 1996-09-10

...BRCA2 loci, as well as being carrier of a BRCA1 germline mutation. Although it seems unlikely that the p53 germline muta...

Somatic and germline mutations of the BRCA2 gene in sporadic ovarian cancer.

Foster(K A),Harrington(P),Kerr(J),Russell(... Cancer Res 1996-09-10

...BRCA2 has recently been isolated. A role for BRCA2 in sporadic breast and ovarian cancer has been suggested by loss of h...

High prevalence of the 999del5 mutation in icelandic breast and ovarian cance...

Johannesdottir(G),Gudmundsson(J),Bergthors... Cancer Res 1996-09-10

...BRCA2 mutation. Here, we report the frequency of the 999del5 BRCA2 mutation in an Icelandic control population and four ...

Genetic heterogeneity in breast cancer susceptibility.

Andersen(T I) Acta Oncol 1996-09-03

...BRCA2 locus at 13q12-q13 appears to be involved in 40-45% of the site-specific breast cancer families, and in most of th...

Isolation of expressed sequences that include a gene for familial breast canc...

Jacob(A N),Kandpal(G),Kandpal(R P) Oncogene 1996-09-04

...BRCA2 mRNA, the sequence of which was published recently (Wooster et al, 1995). Northern analysis of BRCA2 transcripts f...

Confirmation of susceptibility locus on chromosome 13 in Australian breast ca...

Grimmond(S M),Palmer(J M),Walters(M K),Sco... Hum Genet 1996-08-20

...BRCA2 carrier status. Our results confirm the existence of BRCA2 on the long arm of chromosome 13 and support previous f...

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