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THe genetics of familial breast cancer.

Cannon-Albright(L A),Skolnick(M H) Semin Oncol 1996-06-06

...BRCA2, has been localized to chromosome 13q. Positional cloning of this gene is well advanced and analysis of its biolog...

Allelic imbalance on chromosome 13q: evidence for the involvement of BRCA2 an...

Hamann(U),Herbold(C),Costa(S),Solomayer(E ... Cancer Res 1996-06-12

...BRCA2 region but not at RB1. Six tumors showed AI at RB1 but not in the BRCA2 region. AI in the BRCA2 region correlated ...

Allelic loss at chromosome 13q12-q13 is associated with poor prognosis in fam...

van den Berg(J),Johannsson(O),Håkansson(S)... Br J Cancer 1996-12-27

...BRCA2 region was found in 34% and at RBI in 27% of the tumours. Selective LOH at BRCA2 occurred in 7% of the tumours, wh...

Frequent somatic deletion of the 13q12.3 locus encompassing BRCA2 in chronic ...

Garcia-Marco(J A),Caldas(C),Price(C M),Wie... Blood 1996-10-16

...BRCA2 gene, in 80% of 35 CLL cases studied. Homozygous deletion of BRCA2, located within the minimal deletion consensus,...

Familial breast cancer.

Weber(B L) Recent Results Cancer Res 1996-09-25

...BRCA2. Ongoing studies investigating the function of BRCA1, and eventually BRCA2, will lead to a better understanding of...

Genetic heterogeneity in hereditary breast cancer: role of BRCA1 and BRCA2.

Rebbeck(T R),Couch(F J),Kant(J),Calzone(K)... Am J Hum Genet 1996-09-25

...BRCA2. Five families (22%) provided evidence against linkage to both BRCA1 and BRCA2. No BRCA1 or BRCA2 mutations were d...

[Hereditary breast cancers].

Perey(L),Schorderet(D F) Praxis (Bern 1994) 1996-10-24

...BRCA2, clearly responsible for hereditary predisposition of breast carcinoma. Another gene, p53, was also shown to be in...

Loss of heterozygosity in sporadic breast tumours at the BRCA2 locus on chrom...

Cleton-Jansen(A M),Collins(N),Lakhani(S R)... Br J Cancer 1995-12-26

...BRCA2. To investigate the involvement of BRCA2 in sporadic breast cancer 200 breast tumours were tested for LOH on chrom...

Different tumor types from BRCA2 carriers show wild-type chromosome deletions...

Gudmundsson(J),Johannesdottir(G),Bergthors... Cancer Res 1995-12-06

...BRCA2 carriers in five families showing strong evidence of linkage to BRCA2. In addition to high frequency of LOH in fem...

Evidence for the presence of two tumour-suppressor genes for hepatocellular c...

Kuroki(T),Fujiwara(Y),Nakamori(S),Imaoka(S... Br J Cancer 1995-09-21

...BRCA2 locus. These findings suggest that at least one putative tumour-suppressor gene for HCC other than RB, possibly BR...

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