...BRCA2, has been localized to chromosome 13q. Positional cloning of this gene is well advanced and analysis of its biolog...
...BRCA2 region but not at RB1. Six tumors showed AI at RB1 but not in the BRCA2 region. AI in the BRCA2 region correlated ...
...BRCA2 region was found in 34% and at RBI in 27% of the tumours. Selective LOH at BRCA2 occurred in 7% of the tumours, wh...
...BRCA2 gene, in 80% of 35 CLL cases studied. Homozygous deletion of BRCA2, located within the minimal deletion consensus,...
...BRCA2. Ongoing studies investigating the function of BRCA1, and eventually BRCA2, will lead to a better understanding of...
...BRCA2. Five families (22%) provided evidence against linkage to both BRCA1 and BRCA2. No BRCA1 or BRCA2 mutations were d...
...BRCA2, clearly responsible for hereditary predisposition of breast carcinoma. Another gene, p53, was also shown to be in...
...BRCA2. To investigate the involvement of BRCA2 in sporadic breast cancer 200 breast tumours were tested for LOH on chrom...
...BRCA2 carriers in five families showing strong evidence of linkage to BRCA2. In addition to high frequency of LOH in fem...
...BRCA2 locus. These findings suggest that at least one putative tumour-suppressor gene for HCC other than RB, possibly BR...
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