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Thermodynamic Properties of Water Molecules at a Protein-Protein Interaction ...

Huggins(David J),Marsh(May),Payne(Mike C) J Chem Theory Comput 0000-00-00

...BRCA2 to form filaments. X-ray crystallography has determined that the same interface functions in both interactions. Wo...

A Frailty-Model-Based Method for Estimating Age-Dependent Penetrance from Fam...

Choi(Yun-Hee) J Biom Biostat 0000-00-00

...BRCA2 genes is used to illustrate the method.

Population-Calibrated Gene Characterization: Estimating Age at Onset Distribu...

Iversen(Edwin S),Chen(Sining) J Am Stat Assoc 0000-00-00

...BRCA2. The Bayesian analysis that we use incorporates a modified segregation model and prior data on penetrance derived ...

Classification of Missense Mutations of Disease Genes.

Zhou(Xi),Iversen(Edwin S),Parmigiani(Giova... J Am Stat Assoc 0000-00-00

...BRCA2, using data collected at the Duke University Medical Center in Durham, North Carolina.

PARP Inhibitors for the Treatment and Prevention of Breast Cancer.

Vinayak(Shaveta),Ford(James M) Curr Breast Cancer Rep 0000-00-00

...BRCA2 tumors to be highly sensitive to PARP inhibitors as a result of homologous recombination defect. Based on this pre...

Novel BRCA1 deleterious mutation (c.1949_1950delTA) in a woman of Senegalese ...

Diez(Orland),Pelegrí(Amadeu),Gadea(Neus),G... Oncol Lett 0000-00-00

...BRCA2 genetic testing and genetic diversity in BRCA1 and BRCA2 in sub-Saharan African populations. We report a novel mut...

Skp2 is a promising therapeutic target in breast cancer.

Wang(Zhiwei),Fukushima(Hidefumi),Inuzuka(H... Front Oncol 0000-00-00

...BRCA2. Emerging evidence has shown that the F-box protein S-phase kinase associated protein 2 (Skp2) also plays an impor...

Detected, yet not Diagnosed - Breast Cancer Screening with MRI Mammography in...

Heil(Joerg),Czink(Elena),Schipp(Anne),Sohn... Breast Care (Basel) 0000-00-00

...BRCA2 mutation carrier whose breast cancer could have been diagnosed 2 years earlier; this is a rare case of a false-neg...

Genetic testing and first presymptomatic diagnosis in Moroccan families at hi...

Laarabi(Fatima Zahra),Jaouad(Imane Cherkao... Oncol Lett 0000-00-00

Germline mutations in the BRCA1 and BRCA2 genes highly predispose to breast and ovarian cancers and are responsible for ...

Novel sequence variants and common recurrent polymorphisms of BRCA2 in Sri La...

DE Silva(Sumadee),Tennekoon(Kamani H),Karu... Exp Ther Med 0000-00-00

...BRCA2 gene were studied in 149 study participants from the same cohort. There were 55 familial and 54 sporadic breast ca...

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