...BRCA2 are responsible for the majority of hereditary breast and ovarian cancers, and these mutations also increase the r...
...BRCA2), seem to account for a substantial portion of germline mutations in high-risk breast/ovarian cancer families. Amo...
We analyzed 37 primary invasive carcinomas for BRCA1 and BRCA2 mutations by screening the entire coding regions of both ...
...BRCA2, hMLH1, MGMT, and DNMT3B) in tumors from the cases and normal ovaries from the controls. We found that mRNA expres...
...BRCA2, located in the DNA repair pathway, the development of novel techniques was urgently needed to identify low-risk v...
...BRCA2 mutations. We found a novel nonsense (c.2469G>A, p.W823*) mutation in one patient. In addition, we also found 51 m...
The tumor suppressor gene breast cancer susceptibility gene 2 (BRCA2) is frequently mutated or epigenetically repressed ...
...BRCA2 mutation carriers in the Washington Ashkenazi Kin-Cohort Study of Breast Cancer.
...BRCA2 mutation carriers with breast cancer have a high risk of ipsilateral breast cancer tumor recurrence (IBTR) and a h...
...BRCA2 to form filaments. X-ray crystallography has determined that the same interface functions in both interactions. Wo...
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