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TP53 BRCA1 CRISPR single-cell cancer

Kim(Sung Han),Park(Weon Seo),Yun(Soo In),J... Histopathology 0000-00-00

...BRCA2, respectively, in the malignant tissues. The BRCA2 expression differed significantly between BCR-positive and BCR-...

Kinnersley(Ben),Kamatani(Yoichiro),Labussi... Eur J Hum Genet 0000-00-00

...BRCA2:c.9976A>T, p.(Lys3326Ter), which has been shown to influence breast and lung cancer risk (odds ratio (OR)=2.3, P=4...

Caminsky(Natasha G),Mucaki(Eliseos J),Perr... Hum Mutat 0000-00-00

BRCA1 and BRCA2 testing for hereditary breast and ovarian cancer (HBOC) does not identify all pathogenic variants. Seque...

Ivy(S Percy),Liu(Joyce F),Lee(Jung-Min),Ma... Expert Opin Investig Drugs 0000-00-00

...BRCA2 (BRCAm) are most responsive to PARP inhibitors (PARPi). PARPi combined with angiogenesis inhibition improved anti-...

Thirthagiri(Eswary),Klarmann(Kimberly D),S... Hum Mol Genet 0000-00-00

The breast cancer gene, BRCA2, is essential for viability, yet patients with Fanconi anemia-D1 subtype are born alive wi...

Snyder(Carrie) Fam Cancer 0000-00-00

...BRCA2 and the mismatch repair genes associated with Lynch syndrome; the time during which the genes were being discovere...

Revelli(Alberto),Salvagno(Francesca),Delle... Minerva Ginecol 0000-00-00

...BRCA2 gene have a specifically increased lifetime risk of developing breast and tubo-ovarian cancer. Moreover, they are ...

Chay(Wen Yee),McCluggage(W Glenn),Lee(Chen... Int J Gynecol Cancer 0000-00-00

...BRCA2 mutations, or a family history of ovarian or breast cancer before the diagnosis of STIC or HGSC were excluded. A r...

De Toni(Enrico N),Ziesch(Andreas),Rizzani(... Oncotarget 0000-00-00

...BRCA2 gene knockout and a BRCA2 gene complementation model. The effects of TRAIL-R-targeting compounds and ICL-agents on...

Signorelli(Mauro),Bogani(Giorgio),Ditto(An... Minerva Ginecol 0000-00-00

...BRCA2 increase significantly the risk of developing breast and ovarian cancers, and they have been associated with incre...

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