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TP53 BRCA1 CRISPR single-cell cancer

Smith(Miriam J),Urquhart(Jill E),Harkness(... Hum Mutat 0000-00-00

...BRCA2, TP53, MSH2, MLH1, MSH6, PMS2, NF1, NF2, APC, PTCH1, and VHL) representing seven tumor predisposition syndromes in...

Hunter(Sally M),Rowley(Simone M),Clouston(... Urol Oncol 0000-00-00

...BRCA2 mutations. Genotyping was performed for all potentially predisposing variants detected within each family on the a...

Nair(Navya),Bellcross(Cecelia),Haddad(Lisa... J Cancer Educ 0000-00-00

...BRCA2 (BRCA) genes. Identification of individuals with HBOC requires that primary care providers understand the genetic ...

Flisikowski(K),Flisikowska(T),Sikorska(A),... Vet Comp Oncol 0000-00-00

...BRCA2, MC1R, KIT, NRAS and RAD51, associated with predisposition to melanoma, mammary cancer, osteosarcoma and histiocyt...

Thike(Aye A),Tan(Puay H),Ikeda(Murasaki),I... Histopathology 0000-00-00

...BRCA2 and p53 in 699 women with triple-negative breast cancer was investigated using tissue microarrays. The prognostic ...

Kim(Sung Han),Park(Weon Seo),Yun(Soo In),J... Histopathology 0000-00-00

...BRCA2, respectively, in the malignant tissues. The BRCA2 expression differed significantly between BCR-positive and BCR-...

Kinnersley(Ben),Kamatani(Yoichiro),Labussi... Eur J Hum Genet 0000-00-00

...BRCA2:c.9976A>T, p.(Lys3326Ter), which has been shown to influence breast and lung cancer risk (odds ratio (OR)=2.3, P=4...

Caminsky(Natasha G),Mucaki(Eliseos J),Perr... Hum Mutat 0000-00-00

BRCA1 and BRCA2 testing for hereditary breast and ovarian cancer (HBOC) does not identify all pathogenic variants. Seque...

Ivy(S Percy),Liu(Joyce F),Lee(Jung-Min),Ma... Expert Opin Investig Drugs 0000-00-00

...BRCA2 (BRCAm) are most responsive to PARP inhibitors (PARPi). PARPi combined with angiogenesis inhibition improved anti-...

Thirthagiri(Eswary),Klarmann(Kimberly D),S... Hum Mol Genet 0000-00-00

The breast cancer gene, BRCA2, is essential for viability, yet patients with Fanconi anemia-D1 subtype are born alive wi...

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