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RAD51 variant proteins from human lung and kidney tumors exhibit DNA strand e...

Silva(Michelle C),Morrical(Milagros D),Bry... DNA Repair (Amst) 0000-00-00

...BRCA2, and in RAD51 itself, are associated with human breast cancer. Here we describe the properties of two mutations in...

Comprehensive Genomic Profiling Facilitates Implementation of the National Co...

Suh(James H),Johnson(Adrienne),Albacker(Le... Oncologist 0000-00-00

...BRCA2 (2.5%), NRAS (2.3%), BRCA1 (1.7%), MAP2K1 (1.2%), HRAS (0.7%), NTRK1 (0.7%), and NTRK3 (0.2%).,CGP is practical an...

Detection of Germline Mutation in Hereditary Breast and/or Ovarian Cancers by...

Kwong(Ava),Shin(Vivian Y),Au(Chun H),Law(F... J Mol Diagn 0000-00-00

Mutation in BRCA1/BRCA2 genes accounts for 20% of familial breast cancers, 5% to 10% of which may be due to other less p...

RecA: Regulation and Mechanism of a Molecular Search Engine.

Bell(Jason C),Kowalczykowski(Stephen C) Trends Biochem Sci 0000-00-00

...BRCA2 and other tumor suppressors.

Anti-Müllerian hormone serum concentrations of women with germline BRCA1 or B...

Phillips(Kelly-Anne),Collins(Ian M),Milne(... Hum Reprod 0000-00-00

Do women with ITALIC! BRCA1 or ITALIC! BRCA2 mutations have reduced ovarian reserve, as measured by circulating anti-Mül...

Germline Analysis from Tumor-Germline Sequencing Dyads to Identify Clinically...

Seifert(Bryce A),O'Daniel(Julianne M),Amin... Clin Cancer Res 0000-00-00

...BRCA2, CDKN2A, and CHEK2 In contrast, a substantial proportion of patients (178, 40.5%) had Variants of Uncertain Signif...

Determining the frequency of pathogenic germline variants from exome sequenci...

Hart(Steven N),Ellingson(Marissa S),Schahl... BMJ Open 0000-00-00

...BRCA2, FANCL, MSR1, MUTYH, RB1, TSHR and WRN genes. All but one patient opted in to receive clinically actionable result...

Identification of novel BRCA founder mutations in Middle Eastern breast cance...

Bu(Rong),Siraj(Abdul K),Al-Obaisi(Khadija ... Int J Cancer 0000-00-00

...BRCA2 mutations in different populations. The prevalence and effect of BRCA 1 and BRCA 2 mutations in Middle Eastern pop...

Spatial separation of replisome arrest sites influences homologous recombinat...

Willis(Nicholas A),Scully(Ralph) Cell Cycle 0000-00-00

...BRCA2 and Rad51 mediate STGC but suppress LTGC at Tus/Ter-arrested forks. Here, we report the impact of Ter array length...

Fanconi Anemia Proteins Function in Mitophagy and Immunity.

Sumpter(Rhea),Sirasanagandla(Shyam),Fernán... Cell 0000-00-00

...BRCA2, are required for mitophagy. Thus, members of the FA pathway represent a previously undescribed class of selective...

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