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The Cytochrome CYP4 in Breast and Other Cancers.

Calaf(GM),Crispin(LA),Ossandon-Acosta(F),P... Biology (Basel) 2025-07-04

...BRCA2, but a positive correlation with ESR1 in the basal subtype. CYP4F12 has a significant positive correlation with BR...

Two-hit events occurred independently in bilateral breast cancers in a germli...

Semba(R),Eguchi(H),Takatsu(M),Hashizume(T)... Breast Cancer 2025-11-00

...BRCA2 (BRCA1:c.5193 + 2dup, BRCA2:c.6952C > T/p.Arg2318Ter). According to the data from the test, the former was interpr...

SLX1 silencing overcomes Olaparib resistance in metastatic castration-resista...

Zhao(X),Feng(S),Nitie(X),Muluo(S),Lei(Y) Cancer Biol Ther 2025-12-00

...BRCA2 mutations, was used as a cell model for both in vitro and in vivo studies. Elevated SLX1A expression in prostate c...

Benign-malignant breast nodule discrimination model based on age, tumor-assoc...

Yang(X),Yan(T),Wang(Y),Tong(Y),Ma(X),Guo(L... Int J Biol Markers 2025-09-00

...BRCA2, TP53, ATAD2, NY-ESO-1, CAGE) exhibited significant differences (p < 0.001) between benign and malignant breast no...

Ovarian cancer after breast cancer in women with a BRCA1 or BRCA2 pathogenic ...

Apostol(AI),Kotsopoulos(J),Gronwald(J),Kim... Gynecol Oncol 2025-10-00

...BRCA2). The 15-year cumulative ovarian cancer risk was 14.9 % in BRCA1 and 5.1 % in BRCA2 carriers. Women with breast ca...

The TESTBREAST journey: Revisiting the importance of early detection by frequ...

Andour(L),Hagenaars(SC),Vangangelt(K),Aalb... Int J Cancer 2025-08-15

...BRCA2 (n = 29, 29%) carriers. Invasive cancer was diagnosed in 100 cases: 76% (n = 76) had a PV with a median age of 49 ...

Germline BRCA2 Mutation and Lynch Syndrome in a Patient With Multiple Primary...

Puglisi(MM),Dziarnowski(NN),Baralo(B),Vach... Case Rep Oncol Med 2025-00-00

...BRCA2 and PSM2 mutation in the setting of metastatic pancreatic and prostate cancer. Case Presentation: The patient was ...

JPI-547, a Dual Inhibitor of PARP/Tankyrase, Shows Antitumor Activity Against...

Oh(KS),Nam(AR),Bang(JH),Jeong(Y),Choo(SY),... Int J Biol Sci 2025-00-00

...BRCA2-/- PDAC cells. JPI-547 outperformed most PARP inhibitors, with a half-maximal inhibitory concentration approximate...

Potential role of Fanconi anemia pathway in the pathogenesis of endometrial c...

Yao(M),Liu(C),Ping(H),Meng(K),Li(X),Li(Q),... Mol Med Rep 2025-11-00

...BRCA2, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ/BRIP1, FANCL, FANCM, FANCN/PALB2, FANCO/RAD51C, FANCP/SLX4, FANCQ/XPF, ...

Capturing breast cancers&#x27; copy-number landscape in routine pathology: Exploit...

Kramer(CJH),van Wijk(LM),Ruano(D),Gelpke-V... Br J Cancer 2025-11-00

...BRCA2/PALB2 pathogenic variants in the prospective cohort. Moreover, the success rate of the low-resolution testing appr...

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