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Counselling framework for moderate-penetrance cancer-susceptibility mutations...

Tung(Nadine),Domchek(Susan M),Stadler(Zsof... Nat Rev Clin Oncol 0000-00-00

...BRCA2, and those associated with Lynch syndrome). The extrapolation of guidelines for the management of individuals with...

Cancer Incidence in First- and Second-Degree Relatives of BRCA1 and BRCA2 Mut...

Streff(Haley),Profato(Jessica),Ye(Yuanqing... Oncologist 0000-00-00

Mutations in the BRCA1 and BRCA2 genes are associated with increased risk of breast, ovarian, and several other cancers....

Comprehensive mutation profiling of mucinous gastric carcinoma.

Rokutan(Hirofumi),Hosoda(Fumie),Hama(Natsu... J Pathol 0000-00-00

...BRCA2 (9%), BRCA1 (7%), and ERBB3 (6%). RHOA mutation was detected only in 4% of U-MGCs and in no D-MGCs. MYH9 was recur...

[BRCA1/2 gene mutation and clinicopathologic features of triple negative brea...

Ma(Z P),Wang(W),Zhang(W) Zhonghua Bing Li Xue Za Zhi 0000-00-00

...BRCA2 (exon 11) genes using paraffin-embedded tissue samples of 33 TNBC patients (21 Uyghur patients and 12 Han patients...

Founder and Recurrent Mutations in BRCA1 and BRCA2 Genes in Latin American Co...

Ossa(Carlos Andrés),Torres(Diana) Oncologist 0000-00-00

...BRCA2 c.156_157insAlu), and Colombia (BRCA1 3450del4, A1708E, and BRCA2 3034del4) and in Latinas residing in Southern Ca...

B7-H3 upregulates BRCC3 expression, antagonizing DNA damage caused by 5-Fu.

Sun(Zhang Zhang),Zhang(Ting),Ning(Kuan),Zh... Oncol Rep 0000-00-00

...BRCA2-BRCC3 DNA repair complex, had a direct relationship with B7-H3, an immunoglobulin that is upregulated in tumor tis...

New paradigms for BRCA1/BRCA2 testing in women with ovarian cancer: results o...

Plaskocinska(Inga),Shipman(Hannah),Drummon... J Med Genet 0000-00-00

Over recent years genetic testing for germline mutations in BRCA1/BRCA2 has become more readily available because of tec...

Dynamics of chromosomal aberrations, induction of apoptosis, BRCA2 degradatio...

Bergs(Judith W J),Oei(Arlene L),Ten Cate(R... Int J Mol Med 0000-00-00

Hyperthermia can transiently degrade BRCA2 and thereby inhibit the homologous recombination pathway. Induced DNA-double ...

RANKL/RANK control Brca1 mutation-driven mammary tumors.

Sigl(Verena),Owusu-Boaitey(Kwadwo),Joshi(P... Cell Res 0000-00-00

...BRCA2 genes markedly increase the risk for the development of breast cancer. Here, using two different mouse models, we ...

How Far Do We Go With Genetic Evaluation? Gene, Panel, and Tumor Testing.

Lynce(Filipa),Isaacs(Claudine) Am Soc Clin Oncol Educ Book 0000-00-00

...BRCA2 for hereditary breast and ovarian cancer or mismatch repair genes for Lynch syndrome). The decision regarding whic...

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