...Brca2, Nf1, and Rb1), and p53 remained transcriptionally active. Homologous recombination in ID8 remained intact in func...
Pathogenic mutations in BRCA1 and BRCA2 are associated with high risks of breast and ovarian cancer. However, penetrance...
When the BRCA1 and BRCA2 tumour suppressor genes were identified in the early 1990s, the immediate implications of mappi...
Most women diagnosed with unilateral breast cancer without BRCA1 or BRCA2 mutations are at low risk of contralateral bre...
...BRCA2 and POLQ was stronger than those by co-depleting BRCA2 and other TLS factors including POLH, REV3, or REV1. Our re...
...BRCA2 genes by different germline and somatic alterations, and their diagnosis has great significance in targeted tumor ...
...BRCA2), year of birth, and ethnicity were recorded. Paired t-test was used to analyze differences in age at cancer diagn...
...BRCA2, RAD51, XRCC5, XRCC6 and LIG4 genes in bone marrow samples of 47 MDS patients in order to evaluate the association...
...BRCA2, an unexpected excess of functionally pathogenic variants was seen in ERCC2. Probands were more likely than contro...
...BRCA2 gene mutations. Existing, albeit limited, data indicate that risks of breast cancer are not increased with use of ...
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