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Therapeutic options for triple-negative breast cancers with defective homologou…

Jaspers(Janneke E),Rottenberg(Sven),Jonkers(… Biochim Biophys Acta 2009-11-03

...BRCA1-deficient cells. Here, we review the features shared between triple-negative, basal-like and BRCA1-related breast ...

Mismatch DNA-specific enzymatic cleavage employed in a new method for the elect…

Won(Byoung Yeon),Shin(Sung Chul),Chung(Won-y… Chem Commun (Camb) 2009-09-18

...BRCA1 gene.

PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and…

Zhang(Fan),Fan(Qiang),Ren(Keqin),Andreassen(… Mol Cancer Res 2009-12-03

...BRCA1. Analysis of the assembly of foci in these cells by BRCA1, PALB2, BRCA2, and RAD51 suggests that BRCA1 recruits PA...

Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicent…

Rebbeck(Timothy R),Mitra(Nandita),Domchek(Su… Cancer Res 2009-09-25

...BRCA1 and/or BRCA2 may be associated with modified ovarian cancer risk in women who carry BRCA1/2 mutations.

Clinicopathological study of male breast carcinoma: 24 years of experience.

Shah(Parveen),Robbani(Irfan),Shah(Omar) Ann Saudi Med 2009-09-09

...BRCA1 mutation.,An incidence of 4.1% for male breast cancer indicates that this disease is not as uncommon as presumed i...

Tolerability of breast ductal lavage in women from families at high genetic ris…

Loud(Jennifer T),Beckjord(Ellen Burke),Nicho… BMC Womens Health 2009-10-29

...BRCA1/2 mutation-positive and -negative women from an IRB-approved research study.,165 BRCA1/2 mutation-positive, 26 mut...

Methylation and protein expression of DNA repair genes: association with chemot…

Swisher(Elizabeth M),Gonzalez(Rachel M),Tani… Mol Cancer 2009-10-20

...BRCA1 and BRCA2 mediates resistance to platinum chemotherapy in recurrent BRCA1 and BRCA2 mutated hereditary ovarian car...

Low concentrations of diindolylmethane, a metabolite of indole-3-carbinol, prot…

Fan(Saijun),Meng(Qinghui),Saha(Tapas),Sarkar… Cancer Res 2009-09-11

...BRCA1 in carcinoma and normal cell types. Up-regulation of BRCA1 was dose and time dependent, and it was observed at phy...

Elevated level of 8-oxo-7,8-dihydro-2'-deoxyguanosine in leukocytes of BRCA1 mu…

Dziaman(Tomasz),Huzarski(Tomasz),Gackowski(D… Int J Cancer 2009-09-15

Carriers of BRCA1 mutation face highly increased risk of breast and ovarian cancer and some studies with cell culture su...

Cellular and molecular consequences of defective Fanconi anemia proteins in rep…

Thompson(Larry H),Hinz(John M) Mutat Res 2009-09-29

...BRCA1 and may remove structural barriers to replication, such as guanine quadruplex structures, and/or assist in crossli...

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