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Targeting DNA Repair: The Role of PARP Inhibition in the Treatment of Castrat...

Castro(Elena),Mateo(Joaquin),Olmos(David),... Cancer J 0000-00-00

...BRCA2, ATM, PALB2, and other DNA repair genes.We review the current evidence of how this strategy is relevant for the tr...

Effect of BRCA germline mutations on breast cancer prognosis: A systematic re...

Baretta(Zora),Mocellin(Simone),Goldin(Elen... Medicine (Baltimore) 0000-00-00

...BRCA2 mutation carriers have worse BCSS than sporadic/BRCA-negative cases (HR 1.29, 95% CI: 1.03-1.62), although they ha...

BRCA1 allele-specific expression in genetic predisposed breast/ovarian cancer...

Jamard(Estelle),Volard(Bertrand),Dugué(Aud... Fam Cancer 0000-00-00

...BRCA2 deleterious mutation. BRCA1 ASE evaluated on three SNPs among controls and HBOC patients without deleterious mutat...

Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function...

Alavattam(Kris G),Kato(Yasuko),Sin(Ho-Su),... Cell Rep 0000-00-00

...BRCA2 (FANCD1) and SLX4 (FANCP) accumulation on the sex chromosomes during meiosis. In addition, FA proteins modulate di...

Genetic profiling of a rare condition: co-occurrence of albinism and multiple...

De Summa(Simona),Guida(Michele),Tommasi(St... Oncotarget 0000-00-00

...BRCA2), pathogenesis (BRAF, NRAS, PIK3CA, KIT, PTEN), skin/hair pigmentation (MC1R, MITF) and in immune pathways (CTLA4)...

Robust homology-directed repair within mouse mammary tissue is not specifical...

Kass(Elizabeth M),Lim(Pei Xin),Helgadottir... Nat Commun 0000-00-00

...BRCA2, may increase its susceptibility to tumorigenesis incurred by BRCA2 mutation.

Predictive value of ATP7b, BRCA1, BRCA2, PARP1, UIMC1 (RAP80), HOXA9, DAXX, T...

Pontikakis(S),Papadaki(C),Tzardi(M),Trypak... Pharmacogenomics J 0000-00-00

...BRCA2, PARP1, UIMC1(RAP80), HOXA9, DAXX, TXN (TRX1), THBS1 (TSP1) and PRR13 (TXR1) mRNA expression by quantitative real-...

Urological cancer related to familial syndromes.

Costa(Walter Henriques da),Jabboure(George... Int Braz J Urol 0000-00-00

...BRCA2 genes that are known to increase the incidence of high-risk cancer in young patients, new studies have shown mutat...

Genomic profiling is predictive of response to cisplatin treatment but not to...

Wei(Lei),Chintala(Sreenivasulu),Ciamporcer... Oncotarget 0000-00-00

...BRCA2, and CASP8. Furthermore, RNA-Seq analysis revealed the overexpression of cisplatin resistance associated genes suc...

Screening men at increased risk for prostate cancer diagnosis: Model estimate...

Gulati(Roman),Cheng(Heather H),Lange(Paul ... Cancer Epidemiol Biomarkers... 0000-00-00

...BRCA2 mutation carriers (HR=1.05, 95% CI 0.63-1.59 and HR=1.81, 95% CI 1.14-2.78, respectively). Our analysis suggests s...

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