...BRCA2 mutations are deficient in homologous recombination DNA repair and are intrinsically sensitive to platinum therapy...
...Brca2, Brit1, Eif4g3, Hop2, Hormad1, and Rnf212) was significantly reduced in Foxj3 , Stra8-Cre spermatocytes. Thus, we ...
...BRCA2 and RB1. All three cases carried TP53 mutations as revealed by NGS. Moreover, in the whole series, the integrative...
...BRCA2 mutated, 65.3% at BRCA1 and 34.7% at BRCA2 gene. The mutation c.5266dupC (former 5382insC) was the most frequent a...
...BRCA2, RAD51, Rb-related proteins 107 and 130, Tip60, and p16INK4A. Further elucidation of these pathways could lead to ...
...BRCA2, tumor protein 53, erb-b2 receptor tyrosine kinase 2, matrix metalloproteinases and ADAM metallopeptidase domain-c...
...BRCA2 and HOXB13. A comprehensive search of germline variants for patients with PC has not been reported in Japanese fam...
...BRCA2 genes. Here we review current guidelines on breast and ovarian cancer screening, prophylactic surgery, and other r...
...BRCA2 mutations in their tumor. To select patients who may benefit from these treatments, assessment of the mutation sta...
...BRCA2, or PALB2. Double-strand break repair and mismatch repair subtypes were associated with increased expression of an...
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