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TP53 BRCA1 CRISPR single-cell cancer

Kroeger(Paul T),Drapkin(Ronny) Curr Opin Obstet Gynecol 0000-00-00

...BRCA2. Clinical trials have demonstrated successful treatment of homologous recombination-defective cancers with poly-ri...

Arun(B),Atchley(D),Litton(J),Pusztai(L),Va... J Clin Oncol 0000-00-00

...BRCA2 genes account for the major genetic predispositions to breast cancer. BRCA 1 and BRCA2 related breast cancers have...

Karlan(B),Wenzel(L B),Osann(K),Kurz(R),McC... J Clin Oncol 0000-00-00

...BRCA2 (30%) carriers, 40% had a cancer history. The majority of participants were nonHispanic White women (98%) of Ashke...

Kandel(M J),Stadler(Z),Masciari(S),Collins... J Clin Oncol 0000-00-00

...BRCA2 mutations were expected according to the Myriad tables. However, 9 deleterious BRCA1 mutations (39.1%) were found;...

Haffty(B G),Yang(Q),Reiss(M),Kearney(T),Ha... J Clin Oncol 0000-00-00

...BRCA2. Of 8 BRCA1 mutant patients 7 were classified as TN, while only 1 of 6 BRCA2 patients were TN (p < .001).,Patients...

Kauff(N D),Domchek(S M),Friebel(T M),Lee(J... J Clin Oncol 0000-00-00

...BRCA2. To address these limitations, we have pooled our updated datasets to provide robust estimates of the efficacy of ...

Palmieri(G),Colombino(M),Camboni(M G),Manc... J Clin Oncol 0000-00-00

...BRCA2-8765delAG mutation (BRCA2 is also recognized as FANC-D1 gene). Assuming as significant difference in gene expressi...

Tan(D S),Rothermundt Dr(C),Thomas(K),Bancr... J Clin Oncol 0000-00-00

...BRCA2 mutations (BRCA+) were selected from the Royal Marsden Hospital clinical genetics database and matched (1:2) with ...

Kiechle(M),Engel(C),Schmutzler(R), J Clin Oncol 0000-00-00

...BRCA2 mutation carriers (45 yrs) and women tested negative for BRCA1 and BRCA2 mutations (46 yrs) as well as sporadic br...

Bordeleau(L J),Ennis(M),Canon(S),Panchal(S... J Clin Oncol 0000-00-00

...BRCA2 genes account for the majority of hereditary breast and ovarian cancer. Various risk assessment models are availab...

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