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Predictors and prevalence of germ-line BRCA mutations in high-risk patients a...

Riaz(S S),Ahsan(S),Bloom(R E) J Clin Oncol 0000-00-00

190 Background: Germ-line mutations in tumor suppressor genes, BRCA1 and BRCA2, confer high risks of breast and ovarian ...

Risk of breast cancer among Japanese women with a positive family history.

Suzuki(J),Hojo(T),Jimbo(K),Asaga(S),Kinosh... J Clin Oncol 0000-00-00

...BRCA2. However, women with a family history of breast cancer are at increased risk of developing breast cancer compared ...

Identifying genomic rearrangements in BRCA1 and BRCA2 in high-risk individual...

Jackson(M),Mattair(D),Lin(H),Gutierrez-Bar... J Clin Oncol 0000-00-00

...BRCA2 positivity.,Of 172 individuals, 12/34 (35%) had BRCA1 BART mutations, and 7/11 (64%) had BRCA2 BART mutations. Of ...

Assessing the added value of breast tumor markers in breast cancer genetic ri...

Arun(B),Biswas(S),Tankhiwale(N),Blackford(... J Clin Oncol 0000-00-00

...BRCA2 and conditional probabilities of carrying BRCA1 (CondBRCA1) and BRCA2 (CondBRCA2) given a proband is carrier.,The ...

Risk of having BRCA mutations in women with triple-negative breast cancer: A ...

Tun(N M),Villani(G M),Ong(K) J Clin Oncol 0000-00-00

...BRCA2 mutation (BRCA2) has not been found to overrepresent in women with TNBC. We have performed a meta-analysis of thes...

Risk perception in genetic counselling for hereditary breast/ovarian cancer.

Savarese(A),Vigna(C),Sega(F M),Marozzo(B),... J Clin Oncol 0000-00-00

...BRCA2 genes mutation, and then about their eligibility to genetic testing and objective risk as estimated by BRCApro mod...

When the BRCA test is negative-Prevention strategies in women who have no det...

Verma(S),Dent(S F),Paquet(L),Bitonti(L) J Clin Oncol 0000-00-00

...BRCA2), referred to the high risk clinic for screening and prevention advice. Prior to and following genetic testing, pa...

Follow-up MRI screening of BRCA1/2 mutation carriers.

Shah(P),Rosen(M A),Stopfer(J),Siegfried(J ... J Clin Oncol 0000-00-00

...BRCA2 mutation carriers (B1/2). Prophylactic oophorectomy (PO) has been shown to decrease breast cancer (BC) risk in B1/...

Overexpression of a set of genes in mesothelioma versus parietal pleura may e...

Roe(O D),Anderssen(E),Helge(E),Hild Hakvaa... J Clin Oncol 0000-00-00

...BRCA2, FANCA, FANCD2, RAD51) were overexpressed in tumour.,Mesothelioma resistance to therapy is reflected in the gene p...

Higher occurrence of childhood cancer in families with germline mutations in ...

Olsson(H),Magnusson(S),Borg(Å),Nilberth(M)... J Clin Oncol 0000-00-00

...BRCA2 (n=43) MMR (MLH1, MSH2 MSH6) (n=31) and CDKN2A (n=15) genes in comparison with population based control families (...

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