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Frontera(NM),Ahsan(MD),Chandler(IR),Levi(S... Gynecol Oncol 2025-10-00

...BRCA2. Our meta-analysis demonstrates that individuals with melanoma have a pooled OR of 2.84 for carrying a BRCA1 or BR...

Hayashi(T),Konishi(I) World J Oncol 2025-10-00

...BRCA2) 631 3A>T was a VUS. However, this mutation may create a splicing site, which means that the correct BRCA2 mRNA fo...

Philippin(G),Dupaigne(P),Chrabaszcz(É),Itu... Proc Natl Acad Sci U S A 2025-09-16

...BRCA2 in protecting the nascent DNA in human cells, highlighting once again the evolutionary conservation of DNA replica...

Borea(R),Arecco(L),Nardin(S),Chiappe(E),La... Ther Adv Med Oncol 2025-00-00

...BRCA2 genes. Personalized strategies integrating genetic counseling, tailored surveillance and survivorship programs, as...

Crawford(TB),Tayeb(M),Barrett(E),Al-Saleem... medRxiv 2025-08-15

...BRCA2, CHEK2 and Lynch genes were significantly higher compared to two cancer-free male cohorts. BRCA2 and Lynch genes P...

Beutel(AK),Halbrook(CJ),Ekizce(M),Lindenma... United European Gastroenter... 2025-09-00

...BRCA2 and PALB2-defective versus HR-proficient murine PDAC cells, we systematically investigated the feasibility of expa...

Fujii(T) Int J Clin Oncol 2025-10-00

Hereditary breast and ovarian cancer (HBOC) syndrome is caused by germline mutations in the BRCA1 and BRCA2 genes, which...

Ye(Q),Ma(B),Li(L),Wang(Z),Lu(M),Kang(J),Le... Cancer Res 2025-09-15

...BRCA2 facilitated nuclear accumulation of the BRCA2 peptide PROTAC (BPD), thereby promoting BRCA2 degradation in respons...

Hassan(O),Pizzagalli(M),Leary(OP),Zepecki(... J Biol Chem 2025-10-00

...BRCA2 expression and increases cancer cell sensitivity to DNA-damaging agents. These findings reveal the role of HDAC7 i...

Gao(Y),Yao(B),He(S),Zhang(G),Zhang(X),Qi(R... Medicine (Baltimore) 2025-09-12

...BRCA2, CYP2A6, and CHRNA3 as shared causal genes of LUSC on SCLC. This genetic association study provided evidence of a ...