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TP53 BRCA1 CRISPR single-cell cancer

Tatematsu(Kenji),Yoshimoto(Nobuo),Okajima(To… J Biol Chem 2008-06-19

...BRCA1, and RNF8, having the E3 activity, are also down-regulated by interaction with their RING-lacking splice variants ...

Jasper(Melinda J),Liebelt(Jan),Hussey(Nicole… Prenat Diagn 2008-08-18

The risk of breast cancer associated with inheriting a BRCA1 mutation is extremely high, in addition, there is a 50% cha...

Xie(Anyong),Hartlerode(Andrea),Stucki(Manuel… Mol Cell 2008-02-11

Phosphorylated histone H2AX ("gamma-H2AX") recruits MDC1, 53BP1, and BRCA1 to chromatin near a double-strand break (DSB)...

Simeonov(Anton),Yasgar(Adam),Jadhav(Ajit),Lo… Anal Biochem 2008-05-01

...BRCA1, a key tumor suppressor protein with various functions) and phosphorylated proteins (Abraxas/BACH1/CtIP), implicat...

John(Esther M),Miron(Alexander),Gong(Gail),P… JAMA 2008-01-07

...BRCA1 mutation carriers in racial/ethnic minority populations is limited.,To estimate BRCA1 carrier prevalence in Hispan...

Chodick(Gabriel),Struewing(Jeffery P),Ron(El… Eur J Med Genet 2008-06-24

...BRCA1 185delAG mutations were found. Similar frequencies of BRCA1 and BRCA2 mutation carriers were found among Ashkenazi...

Grant(Stephen G),Das(Rubina),Cerceo(Christin… Pathol Oncol Res 2008-05-05

Homozygous loss of activity at the breast cancerpredisposing genes BRCA1 and BRCA2 (FANCD1) confers increased susceptibi...

Foulkes(William D) Nat Genet 2008-01-18

...BRCA1-mutation carriers.

Chetrit(Angela),Hirsh-Yechezkel(Galit),Ben-D… J Clin Oncol 2008-01-29

...BRCA1 and BRCA2 carriers compared with noncarriers. During the study period (median follow-up, 6.2 years), being a BRCA1...

Malacrida(Sandro),Agata(Simona),Callegaro(Mo… J Clin Oncol 2008-01-29

A growing number of sequence changes of unknown clinical significance are being identified in the BRCA1 gene. However, t...

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