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Melan(K),Loap(P),Kirova(Y) Cancers (Basel) 2025-10-09

...BRCA2 mutations. Germline mutations in BRCA2 and BRCA1 were reported in approximately 1 and 2% of male cases, respective...

Sundaresan(I),Palanisamy(N),Saraswathy(R) Genes Environ 2025-10-09

...BRCA2 remain important, smoking-particularly long-term and heavy use-emerges as a modifiable risk factor that needs deep...

Ammous-Boukhris(N),Abdelmaksoud-Dammak(R),... BMC Cancer 2025-10-09

...BRCA2 significantly contribute to ovarian tumorigenesis. This study investigates the genetic landscape of Tunisian patie...

Al-Moundhri(M S),Al-Ansari(A),Al-Mawali(K)... Gulf J Oncolog 2016-04-23

...BRCA2 genes are rare in sporadic cases compared with hereditary cases, molecular alterations, such as loss of heterozygo...

Nomizu(Tadashi),Matsuzaki(Masami),Katagata... Breast Cancer 2016-06-02

...BRCA2 genes was transmitted to the paternal cousin, and the same BRCA2 mutation to the younger sister with bilateral bre...

Garre(P),Martín(L),Sanz(J),Romero(A),Tosar... Clin Genet 2016-02-02

...BRCA2 in 48 FCCX probands. We identified 29 variants including a frameshift mutation. Deleterious variant c.3847_3848del...

Abdollahian(Mehrnaz),Das(Tapas K) IEEE J Biomed Health Inform 2016-01-05

...BRCA2 mutation carriers at age 30, the cost-optimal strategy is PO at age 30, PM at age 40, and yearly screening only af...

Peixoto(A),Santos(C),Pinto(P),Pinheiro(M),... Clin Genet 2016-03-02

...BRCA2 mutations and 526 tested only for the most common mutations. Of the 119 families with pathogenic mutations, 40 (33...

Dörsam(Bastian),Wu(Ching-Fen),Efferth(Thom... Arch Toxicol 2016-01-15

...BRCA2 and Rad51, which are essentials players of homologous recombination (HR)-mediated repair, were treated with 1,8-ci...

Phillips(Tracie D),Richardson(Molly),Cheng... Arch Toxicol 2016-02-16

...Brca2 were significantly lower in liver tumor tissue compared to non-tumor tissue. Expressions of proteins involved in a...