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AIDIT and IMPACT: building research collaborations in targeted prostate cancer …

Doherty(R),Lubinski(J),Manguoglu(E),Luleci(G… J BUON 2007-03-22

...BRCA1/2 mutation carriers and controls), an international team investigating screening and diagnosis for men with a gene...

Light chain 1 of microtubule-associated protein 1B can negatively regulate the …

Lerch-Gaggl(Alexandra F),Sun(Kai),Duncan(Ste… J Biol Chem 2007-05-31

...BRCA1 C-terminal domain, a structural motif that has been shown to facilitate protein-protein interactions, suggesting t...

E2F6 negatively regulates ultraviolet-induced apoptosis via modulation of BRCA1.

Yang(W-W),Wang(Z-H),Zhu(Y),Yang(H-T) Cell Death Differ 2007-07-24

...BRCA1 expression and cleavage, accompanied with increases of the full-length BRCA1 and BRCA1 nuclear foci. In contrast, ...

Vimentin and laminin expression is associated with basal-like phenotype in both…

Rodríguez-Pinilla(Socorro María),Sarrió(Davi… J Clin Pathol 2007-10-16

To determine whether basal-like phenotype and vimentin and/or laminin are related in both sporadic/familial (BRCA1 or BR...

Basal repression of BRCA1 by multiple E2Fs and pocket proteins at adjacent E2F …

Bindra(Ranjit S),Glazer(Peter M) Cancer Biol Ther 2007-05-03

...BRCA1 in cancer cells. Here, we report that multiple E2Fs and associated factors bind the BRCA1 promoter at two adjacent...

Ethical issues in cancer genetics: I 1) whose information is it?

Schneider(Katherine A),Chittenden(Anu B),Bra… J Genet Couns 2007-04-20

...BRCA1 mutation to a patient's relative, who is at 50% risk? Case 4: Do we have an obligation to reveal that a patient is...

Genomic analysis of the 8p11-12 amplicon in familial breast cancer.

Melchor(Lorenzo),Garcia(Maria J),Honrado(Emi… Int J Cancer 2007-02-05

...BRCA1, BRCA2 and non-BRCA1/2 gene mutations. We detected 9 out of 80 familial tumors with this amplicon by chromosomal c...

Risk communication in completed series of breast cancer genetic counseling visi…

Pieterse(Arwen H),van Dulmen(Sandra),van Dij… Genet Med 2007-02-01

...BRCA1/2 mutation, who fulfilled criteria for DNA testing. We developed a checklist for assessing risk communication and ...

Association between clinical characteristics and risk-reduction interventions i…

Uyei(Anne),Peterson(Susan K),Erlichman(Julie… Cancer 2007-02-12

Women who are at increased risk for breast and ovarian cancers, especially BRCA1 and BRCA2 mutation carriers, face a myr...

Management of BRCA1/2 associated breast cancer: a systematic qualitative review…

Liebens(Fabienne Patricia),Carly(Birgit),Pas… Eur J Cancer 2007-04-09

The optimal clinical management of breast cancer (BC) arising in BRCA1/2 mutations carriers is a difficult issue complic...

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