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Iida(K),Urabe(F),Matsui(Y),Tashiro(K),Yosh... NPJ Precis Oncol 2026-02-26

...BRCA2 pathogenic variants (P = 0.008). Within BRCA2-altered cases, BRCA2 loss was associated with the most favorable OS ...

Mhaskar(A),Sleddens-Linkels(E),Liang(I),Ho... Front Cell Dev Biol None

...BRCA2, RAD51 loading was also critical for robust DMC1 recruitment to DSBs. After initial recruitment, we observed a gra...

Beziaud(L),Minasyan(A),Chiang(CL),Soukarie... iScience 2026-07-17

...Brca2-impairs the effectiveness of a dendritic cell-based cancer vaccine (OCDC). OCDC vaccine reduced tumor growth and i...

Chen(JL),Kang(ML),Lin(CJ),Lo(YH),Chen(YJ),... Am J Hum Genet 2026-08-06

...BRCA2 and MLH1 suggest recurrent selective trade-offs in DNA repair genes. Phenome-wide association analysis across 30 h...

Dell'Elice(A),Palmarini(C),Anaclerio(F),Pi... J Med Genet 2026-07-24

...BRCA2. Nevertheless, a substantial proportion of individuals with strong familial cancer aggregation remain genetically ...

Li(W),Wu(B),Gao(B),Irvin(EM),Ghosh(A),Elia... Nat Commun 2026-07-23

...BRCA2 interactor and characterize it as an ssRNA-specific R-loop resolvase. BRCA2 enhances HELZ helicase activity and pr...

Abbas(SH),Wu(J),Shi(T) Comput Methods Programs Biomed 2026-07-30

...BRCA2, GenixRL achieved the best performance and ranked highest on 14 of 17 clinically significant genes in a zero-shot ...

Lu(S),Huang(J),Gu(Y),Wang(C),Shen(K),Fei(X... Endocr Relat Cancer 2026-08-01

...BRCA2 (9.6%). A higher TIL density was observed in TP53-wild-type, low-TMB or low-CNA tumors (P < 0.05). PIK3CA mutation...

Lu(L),Xu(J),Shi(Z),Engelmann(V),Tran(H),We... Prostate Cancer Prostatic D... 2026-08-04

...BRCA2, MSH6, PALB2) were individually associated with increased PCSM and were defined as Tier-1. Aggregated PVs in seven...

Rodríguez-Olivares(JL),Aguilar-Y-Méndez(D)... PLoS One None

...BRCA2, 1 BRIP1, and 1 PALB2). Additionally, one individual harbored a monoallelic PV in MUTYH. The Amsterdam II criteria...