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Ubiquitination and proteasome-mediated degradation of BRCA1 and BARD1 during st…

Lu(Yunzhe),Amleh(Asma),Sun(Jianlong),Jin(Xua… Mol Endocrinol 2007-05-22

...BRCA1 predispose women to early-onset, familial breast and ovarian cancers. However, BRCA1 expression is not restricted ...

Reproductive risk factors for ovarian cancer in carriers of BRCA1 or BRCA2 muta…

McLaughlin(John R),Risch(Harvey A),Lubinski(… Lancet Oncol 2007-03-27

...BRCA1 or BRCA2 genes.,We did a matched case-control study in women who were found to carry a pathogenetic mutation in BR...

The BRCT domain of mammalian Pes1 is crucial for nucleolar localization and rRN…

Hölzel(Michael),Grimm(Thomas),Rohrmoser(Mich… Nucleic Acids Res 2007-03-12

...BRCA1 C-terminal) within Pes1 is quite unique for an rRNA processing factor, as this domain is normally found in factors...

Lack of germ-line promoter methylation in BRCA1-negative families with familial…

Chen(Ying),Toland(Amanda E),McLennan(Jane),F… Genet Test 2007-04-02

...BRCA1 gene for promoter methylation among 41 BRCA1- and BRCA2-negative women whose personal and family histories indicat...

Alternative splicing of breast cancer associated gene BRCA1 from breast cancer …

Lixia(Miao),Zhijian(Cao),Chao(Shen),Chaojian… J Biochem Mol Biol 2007-05-02

...BRCA1 were cloned from breast cancer cell line ZR-75-30 by RT-PCR method. Sequence analysis showed that nine BRCA1 splic...

Multicenter comparative multimodality surveillance of women at genetic-familial…

Sardanelli(Francesco),Podo(Franca),D'Agnolo(… Radiology 2007-03-27

...BRCA1 or BRCA2 mutation carriers, first-degree relatives of BRCA1 or BRCA2 mutation carriers, or women enrolled because ...

A survey of preventive measures among BRCA1 mutation carriers from Poland.

Gronwald(J),Byrski(T),Huzarski(T),Cybulski(C… Clin Genet 2007-04-11

Among women with a BRCA1 mutation, the lifetime risks of breast and ovarian cancer are elevated. Several measures for re...

Contribution of BRCA1 and BRCA2 germline mutations to the incidence of early-on…

Loizidou(M),Marcou(Y),Anastasiadou(V),Newbol… Clin Genet 2007-04-11

...BRCA1 and BRCA2 genes were sequenced using cycle sequencing. We identified four pathogenic mutations: two in BRCA1 [c.18...

Reduced mammographic density with use of a gonadotropin-releasing hormone agoni…

Weitzel(Jeffrey N),Buys(Saundra S),Sherman(W… Clin Cancer Res 2007-04-24

...BRCA1 mutation (BRCA1(mut)) need risk reduction options beyond mastectomy and oophorectomy. We evaluated the efficacy, s...

Estimating risk of breast cancer in carriers of BRCA1 and BRCA2 mutations: a me…

Fu(Rongwei),Harris(Emily L),Helfand(Mark),Ne… Stat Med 2007-05-29

...BRCA1 and BRCA2 mutations are estimated to be 8.39 per cent (6.56, 10.68 per cent) and 2.66 per cent (1.85, 3.82 per cen...

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