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Pölsler(Laura),Fiegl(Heidi),Wimmer(Kathari... Eur J Hum Genet 2016-10-07

Screening for founder mutations in BRCA1 and BRCA2 has been discussed as a cost-effective testing strategy in certain po...

Xu(Lingyun),Zhao(Yansheng),Chen(Zhiqiang),... Breast Cancer 2016-04-25

...BRCA2, the present meta-analysis was addressed to determine whether adjuvant tamoxifen treatment for breast cancer is as...

Stukova(Marina),Hall(Matthew D),Tsotsoros(... J Inorg Biochem 2016-03-14

...BRCA2 mutations were hypersensitive to the PARP inhibitors olaparib and velaparib, but all other cell lines expressing f...

Klonowska(Katarzyna),Ratajska(Magdalena),C... Sci Rep 2016-03-28

...BRCA2. One of the most extensively studied candidates for breast and/or ovarian cancer susceptibility is BARD1. Although...

Trujillano(Daniel),Weiss(Maximilian E R),S... J Mol Diagn 2016-04-25

...BRCA2 mutations and polymorphisms. Genomic DNA was amplified using the Ion AmpliSeq BRCA1 and BRCA2 panel. The DNA Libra...

Gu(Yunyan),Zhang(Mengmeng),Peng(Fuduan),Fa... Oncotarget 2016-01-15

...BRCA2 (BRCA1/2) have a better prognosis than BRCA1/2 alteration non-carriers. However, patients with wild-type BRCA1/2 m...

Rosenthal(E T),Bowles(K R),Pruss(D),van Ka... Clin Genet 2016-08-31

...BRCA2 and MSH2 that are predicted to disrupt splicing, prematurely truncate the protein, or remove the start codon were ...

Gumaste(P V),Penn(L A),Cymerman(R M),Kirch... Br J Dermatol 2016-03-07

...BRCA2 mutations have been linked to melanoma in large breast and ovarian cancer families, though a statistically signifi...

Pettapiece-Phillips(Rachael),Narod(Steven ... Cancer Causes Control 2016-03-29

...BRCA2 gene and thereby normalize protein levels, contribute to stem cell homeostasis, and/or affect hormone levels, migh...

Sociali(Giovanna),Galeno(Lauretta),Parenti... Eur J Med Chem 2016-06-14

...BRCA2-deficient Capan-1 cells and cooperate with gemcitabine to the killing of pancreatic cancer cells. In conclusion, n...