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Genomic hallmarks of homologous recombination deficiency in invasive breast c...

Manié(Elodie),Popova(Tatiana),Battistella(... Int J Cancer 2016-05-31

...BRCA2 or RAD51C confirmed this prediction in 75% (12/16) of the tested cases. In 14% (6/43) of tumors occurring in BRCA1...

Effects of aluminium chloride and aluminium chlorohydrate on DNA repair in MC...

Farasani(A),Darbre(P D) J Inorg Biochem 2016-10-11

...BRCA2, CHK1, CHK2, Rad51, ATR) were also observed using real-time RT-PCR. Loss of BRCA1 or BRCA2 gene function has long ...

[CHEK2-mutation in Dutch breast cancer families: expanding genetic testing fo...

Adank(Muriel A),Hes(Frederik J),van Zelst-... Ned Tijdschr Geneeskd 2016-04-18

...BRCA2 mutations and the genetic cause of breast cancer remains unexplained. Routine testing for the CHEK2*1100delC mutat...

DNA double strand break repair defect and sensitivity to poly ADP-ribose poly...

Weaver(Alice N),Cooper(Tiffiny S),Rodrigue... Oncotarget 2016-08-15

...BRCA2, key factors for non-homologous end joining and homologous recombination respectively. Importantly, the apparent D...

Moreton Lecture: Imaging in the Age of Precision Medicine.

Thrall(James H) J Am Coll Radiol 2016-07-11

...BRCA2 genes. Imaging is poised to play major roles in the age of precision medicine. The imaging community needs to lear...

Exome sequencing reveals frequent deleterious germline variants in cancer sus...

Ellingson(Marissa S),Hart(Steven N),Kalari... Breast Cancer Res Treat 2016-06-01

...BRCA2 (n = 8), CHEK2 (n = 2), FANCA (n = 1), FANCI (n = 1), FANCL (n = 1), FANCM (n = 1), FH (n = 1), MLH3 (n = 1), MUTY...

Prevalence of PALB2 mutations in Australian familial breast cancer cases and ...

Thompson(Ella R),Gorringe(Kylie L),Rowley(... Breast Cancer Res 2016-04-21

...BRCA2. However, large studies that have evaluated the full gene rather than just the most common variants in both cases ...

SNP Set Association Testing for Survival Outcomes in the Presence of Intrafam...

Leclerc(Martin),,Simard(Jacques),Lakhal-Ch... Genet Epidemiol 2016-03-10

...BRCA2.

A model for estimating ovarian cancer risk: application for preventive oophor...

Giannakeas(Vasily),Sopik(Victoria),Shestop... Gynecol Oncol 2016-02-08

...BRCA2.

High response rates to neoadjuvant platinum-based therapy in ovarian cancer p...

Gorodnova(Tatiana V),Sokolenko(Anna P),Iva... Cancer Lett 2016-03-16

...BRCA2 mutation carriers were identified. Complete clinical response was documented in 12/35 (34%) mutation carriers and ...

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