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Gene mutations in gastric cancer: a review of recent next-generation sequenci...

Lin(Y),Wu(Z),Guo(W),Li(J) Tumour Biol 2016-02-02

...BRCA2), chromatin remodeling (ARID1A), cell adhesion (CDH1, FAT4, CTNNA1), cytoskeleton and cell motility (RHOA), Wnt pa...

A targeted approach to genetic counseling in breast cancer patients: the expe...

La Verde(Nicla),Corsi(Fabio),Moretti(Anna)... Tumori 2016-07-11

...BRCA2 mutation. After genetic test results, the available options for treatment/surveillance were discussed by a multidi...

High burden of copy number alterations and c-MYC amplification in prostate ca...

Castro(E),Jugurnauth-Little(S),Karlsson(Q)... Ann Oncol 2016-08-18

...BRCA2 carriers.,The relative high amount of CNAs in morphologically normal prostate tissue of BRCA2 carriers implies a f...

Copy number profiling by array comparative genomic hybridization identifies f...

Biesma(Hedde D),Schouten(Philip C),Lacle(M... Genes Chromosomes Cancer 2016-07-22

...BRCA2-like or non-BRCA-like profiles using previous classifiers derived from FBC, and correlated these profiles with pat...

The role of germline mutations in the BRCA1/2 and mismatch repair genes in me...

Maia(Sofia),Cardoso(Marta),Paulo(Paula),Pi... Fam Cancer 2016-10-05

...BRCA2 founder mutation. None of the alterations were identified in 288 control subjects. Furthermore, we reviewed the 62...

A novel BRCA2 in frame deletion in a Tunisian woman with early onset sporadic...

Hadiji-Abbes(N),Trifa(F),Choura(M),Khabir(... Pathol Biol (Paris) 2016-07-01

...BRCA2 mutation spectrum in Tunisian young women with breast cancer.,Screening the BRCA2 gene was performed using DHPLC, ...

Differential DNA repair pathway choice in cancer cells after proton- and phot...

Fontana(Andrea O),Augsburger(Marc A),Gross... Radiother Oncol 2016-06-10

...BRCA2-deficient ovarian carcinoma cells were hypersensitive toward proton- in comparison with photon-irradiation.,A diff...

Silencing of BRCA2 to Identify Novel BRCA2-regulated Biological Functions in ...

Moro(Loredana),Guaragnella(Nicoletta),Gian... J Vis Exp 2016-03-22

...BRCA2 in human cells offers a valuable strategy to disrupt BRCA2 function in cells with intact BRCA2, including tumor ce...

Living With Genetic Vulnerability: a Life Course Perspective.

Hamilton(Rebekah J),Innella(Nancy A),Bound... J Genet Couns 2016-09-29

...BRCA2 gene mutation long after the initial diagnosis. These women's experiences across time reflect the concepts of the ...

CSN and CAVA: variant annotation tools for rapid, robust next-generation sequ...

Münz(Márton),Ruark(Elise),Renwick(Anthony)... Genome Med 2016-05-19

...BRCA2 gene mutations from a clinical pipeline gave 100 % concordance with Sanger data; only 8/25 BRCA2 mutations were co...

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