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Prakash(Rohit),Zhang(Yu),Feng(Weiran),Jasi... Cold Spring Harb Perspect Biol 2016-01-25

...BRCA2, key players at different stages of HR, are frequently mutated in familial breast and ovarian cancers. Other HR pr...

Jervis(Sarah),Song(Honglin),Lee(Andrew),Di... J Med Genet 2016-03-15

Although BRCA1 and BRCA2 mutations account for only ∼27% of the familial aggregation of ovarian cancer (OvC), no OvC ris...

de Juan(Inmaculada),Palanca(Sarai),Domenec... Fam Cancer 2016-08-26

...BRCA2 mutations. BRCA2 mutation-carriers were associated with families with at least one MBC and one BC in female (type ...

Schroeder(Christopher),Faust(Ulrike),Sturm... Breast Cancer Res Treat 2016-03-04

...BRCA2 (27/620), 0.97 % in CHEK2 (6/620), 0.65 % in ATM (4/620), 0.48 % in CDH1 (3/620), 0.32 % in PALB2 (2/620), 0.32 % ...

Menes(Tehillah S),Terry(Mary Beth),Goldgar... Breast Cancer Res Treat 2016-02-24

BReast CAncer genes 1 and 2 (BRCA1 and BRCA2) mutation carriers diagnosed with breast cancer are at increased risk of de...

Klonowska(Katarzyna),Ratajska(Magdalena),C... Sci Rep 2016-03-28

...BRCA2. One of the most extensively studied candidates for breast and/or ovarian cancer susceptibility is BARD1. Although...

Arun(Banu),Akar(Ugur),Gutierrez-Barrera(An... Int J Oncol 2016-03-21

...BRCA2 genes. In this study, we investigated the antiproliferative effects and mechanism of PARP inhibitors ABT-888 (Veli...

Janatova(Marketa),Soukupova(Jana),Stribrna... PLoS One 2016-04-25

...BRCA2 negative OC patients, to evaluate the frequency of hereditary RAD51C and RAD51D variants in Czech population. The ...

Higgs(J E),Harkness(E F),Bowers(N L),Howar... J Med Genet 2016-06-02

...BRCA2, only 43/3245 (1.3%) carried BRCA2 c.9976A>T alone, after excluding individuals with BRCA2c.6275_6276delTT (n=22) ...

Uehara(Yuriko),Oda(Katsutoshi),Ikeda(Yuji)... PLoS One 2016-05-02

...BRCA2 (62%) coexisted with LOH of RB1 and TP53. Microarray analysis classified CCCs into three clusters. One cluster (CC...