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Risk factors for endometrial cancer among women with a BRCA1 or BRCA2 mutatio...

Segev(Yakir),Rosen(Barry),Lubinski(Jan),Gr... Fam Cancer 2016-06-10

...BRCA2 mutation were identified from a registry of mutation carriers. Cases were 83 women who had a diagnosis of endometr...

BRCA1 and BRCA2 mutations in ethnic Lebanese Arab women with high hereditary ...

El Saghir(Nagi S),Zgheib(Nathalie K),Assi(... Oncologist 2016-04-25

...BRCA2 mutations because of presentation at young age and/or positive family history (FH) of breast or ovarian cancer wer...

Breast self-examination education for BRCA mutation carriers by clinical nurs...

Visser(Annemiek),Bos(Wilmy C A M),Prins(Ju... Clin Nurse Spec 2016-10-20

Breast self-examination (BSE) may be beneficial for women with a BRCA1 or BRCA2 mutation. Therefore, these women are oft...

Two PALB2 germline mutations found in both BRCA1+ and BRCAx familial breast c...

Downs(Bradley),Kim(Yeong C),Xiao(Fengxia),... Breast Cancer Res Treat 2016-01-25

Partner and localizer of BRCA2 (PALB2), plays an important functional role in DNA damage repair. Recent studies indicate...

Homologous recombination and human health: the roles of BRCA1, BRCA2, and ass...

Prakash(Rohit),Zhang(Yu),Feng(Weiran),Jasi... Cold Spring Harb Perspect Biol 2016-01-25

...BRCA2, key players at different stages of HR, are frequently mutated in familial breast and ovarian cancers. Other HR pr...

Endometrial cancers in mutation carriers from hereditary breast ovarian cance...

Casey(Murray Joseph),Bewtra(Chhanda),Lynch... Int J Gynecol Cancer 2016-02-01

...BRCA2. Invasive cancers were registered in 101 mutation carriers with complete pathology reports. Efforts were made to s...

Evaluating the effectiveness of cancer drug sensitization in vitro and in viv...

Rytelewski(Mateusz),Buensuceso(Adrian),Leo... J Vis Exp 2016-05-31

...BRCA2 inhibition as a means to sensitize tumor cells to the DNA damaging drug cisplatin. Tumor cell metabolism (acidific...

In vitro and in vivo correlates of physiological and neoplastic human Fallopi...

Yamamoto(Yusuke),Ning(Gang),Howitt(Brooke ... J Pathol 2016-08-10

...BRCA2 mutations have documented a pre-metastatic intramucosal neoplasm that is found almost exclusively in the Fallopian...

miRNA expression patterns in normal breast tissue and invasive breast cancers...

Vos(Shoko),Vesuna(Farhad),Raman(Venu),van ... Oncotarget 2016-08-18

...BRCA2 mutation carriers. miRNA profiles of 17 BRCA1- and 9 BRCA2-associated breast carcinomas were analyzed using microa...

Identification of germline genetic mutations in patients with pancreatic cancer.

Salo-Mullen(Erin E),O'Reilly(Eileen M),Kel... Cancer 2016-04-04

...BRCA2 mutation and the mean age at diagnosis in BRCA2 carriers was equivalent to that of individuals who were not mutati...

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