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In vitro and in vivo correlates of physiological and neoplastic human Fallopi...

Yamamoto(Yusuke),Ning(Gang),Howitt(Brooke ... J Pathol 2016-08-10

...BRCA2 mutations have documented a pre-metastatic intramucosal neoplasm that is found almost exclusively in the Fallopian...

miRNA expression patterns in normal breast tissue and invasive breast cancers...

Vos(Shoko),Vesuna(Farhad),Raman(Venu),van ... Oncotarget 2016-08-18

...BRCA2 mutation carriers. miRNA profiles of 17 BRCA1- and 9 BRCA2-associated breast carcinomas were analyzed using microa...

RAD51 and BRCA2 Enhance Oncolytic Adenovirus Type 5 Activity in Ovarian Cance...

Tookman(Laura A),Browne(Ashley K),Connell(... Mol Cancer Res 2016-10-18

...BRCA2-mutant and wild-type HGSOC cells, it was demonstrated that intact HR function promotes viral DNA replication and a...

Reevaluation of the BRCA2 truncating allele c.9976A > T (p.Lys3326Ter) in a f...

Thompson(Ella R),Gorringe(Kylie L),Rowley(... Sci Rep 2016-08-22

...BRCA2, has a large number of genetic variants of unknown effect. The variant rs11571833, an A > T transversion in the fi...

Identification of germline genetic mutations in patients with pancreatic cancer.

Salo-Mullen(Erin E),O'Reilly(Eileen M),Kel... Cancer 2016-04-04

...BRCA2 mutation and the mean age at diagnosis in BRCA2 carriers was equivalent to that of individuals who were not mutati...

The History of Patenting Genetic Material.

Sherkow(Jacob S),Greely(Henry T) Annu Rev Genet 2016-09-19

...BRCA2, two genes critical to assessing early-onset breast and ovarian cancer risk, and with a particularly controversial...

Uptake of risk-reducing salpingo-oophorectomy among female BRCA mutation carr...

Kim(Se Ik),Lim(Myong Cheol),Lee(Dong Ock),... J Cancer Res Clin Oncol 2016-05-17

...BRCA2 mutation carriers at the National Cancer Center of Korea.,Between April 2007 and December 2014, 450 women underwen...

BRCA1 and BRCA2 mutations in Japanese patients with ovarian, fallopian tube, ...

Sakamoto(Ikuko),Hirotsu(Yosuke),Nakagomi(H... Cancer 2016-06-06

The contribution of BRCA1 and BRCA2 to ovarian cancer in Japanese patients is still unclear. This study investigated the...

Molecular signature of pancreatic adenocarcinoma: an insight from genotype to...

Sahin(Ibrahim H),Iacobuzio-Donahue(Christi... Expert Opin Ther Targets 2016-09-29

...BRCA2 genes and their role in pancreatic cancer treatment are elaborated upon. We further review recent genomic studies ...

Optimal surgical management for high-risk populations.

King(Tari A),Pilewskie(Melissa),Morrow(Mon... Breast 2016-08-23

...BRCA2 are frequently considered to be at highest risk of local failure, leading to speculation that more-aggressive surg...

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