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TP53 BRCA1 CRISPR single-cell cancer

Komenaka(Ian K),Nodora(Jesse N),Madlensky(... J Community Genet 2016-07-26

...BRCA2. Our experience shows that it is possible to offer GCRA and genetic testing even in the setting of limited resourc...

Yablonski-Peretz(Tamar),Paluch-Shimon(Shan... Breast Cancer Res Treat 2016-10-13

...BRCA2 (8 non-founder mutations), and one each in the RAD51C and CHEK2 genes. Furthermore, actionable mutations were dete...

Walsh(Christine S),Hodeib(Melissa) Curr Opin Obstet Gynecol 2016-09-30

...BRCA2, or other important genes in the DNA repair process of homologous recombination. Sporadic ovarian cancers can also...

Ferzoco(Raina M),Ruddy(Kathryn J) Curr Oncol Rep 2016-10-25

...BRCA2 mutations, family history, age, androgen/estrogen imbalance, and environmental exposures may predispose to male br...

van den Broek(Alexandra J),van 't Veer(Lau... J Clin Oncol 2016-06-09

...BRCA2: 17.2%) compared with 12.6% (BRCA1: 15.6%; BRCA2: 7.2%) for those 41 to 49 years of age (P = .02); our review of p...

Lundberg(Jordan),Reardon(Joshua),Blazer(Ma... Med Oncol 2016-09-07

...BRCA2).

Bernards(Sarah S),Norquist(Barbara M),Harr... Gynecol Oncol 2016-06-01

...BRCA2, BRIP1, MLH1, MSH2, MSH6, PALB2, PMS2, RAD51D, and RAD51C) and additional candidate genes in DNA repair (ATM, BAP1...

Navrátil(J),Fabian(P),Palácová(M),Petrákov... Klin Onkol 2016-02-11

...BRCA2.,The objective of this review is to provide comprehensive information about current knowledge of triple negative b...

Phan(Nhan Lu-Chinh),Trinh(Ngu Van),Pham(Ph... Onco Targets Ther 2016-01-05

...BRCA2, p15, p16, p53, and PTEN, and antitumor drug resistance.,DAC treatment caused significant BCSC differentiation. BC...

Bell-McGuinn(Katherine M),Konner(Jason A),... Int J Gynecol Cancer 2016-10-31

The aim of the study was to evaluate the activity and tolerability of iniparib monotherapy in women with BRCA1 or BRCA2-...

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