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A Successful Multimodal Treatment for High-Grade Serous Ovarian Cancer with B...

Chu(HH),Liu(FY),Wang(CC),Lin(MC),Lai(CH) Case Rep Oncol None

...BRCA2 heterozygous deletion), which was controlled by adjuvant radiotherapy combined with nivolumab and nab-paclitaxel, ...

BRCA2-deficient endothelium: a hidden catalyst in angiotensin II-induced vasc...

Singh(A),Bu(S),Perron(AV),Bhatt(KS),Sandhu... J Hypertens 2026-10-01

...BRCA2 ) are well known to increase the risk of breast and ovarian cancers. Emerging evidence indicates that BRCA2 mutati...

Association of BRCA2 protein expression by immunohistochemistry with biochemi...

Morozumi(K),Nakamura(Y),Oikawa(M),Iwamura(... Urol Oncol 2026-09-00

...BRCA2 alterations have been associated with aggressive disease, the clinical significance of BRCA2 protein expression fo...

Identifying and characterizing the germinal genetic landscape of men with pro...

Svirsky(R),Sonnenfeld(B),Kedar(I),Linial(M... Genet Med Open None

...BRCA2, ATM, NF1, and MSH6), and 21 (7.2%) had risk allele variants. One-third (33%) of the disease-causing or likely dis...

Recent Advances in Genetic Testing and Clinical Management of Hereditary Brea...

Sherigar(P),Kedlaya Herga(S),Pai(A),Mailan... Cancer Med 2026-07-00

...BRCA2 genes. Yet, the role of other cancer susceptibility genes highlights the genetic etiology of HBOC as complex, thus...

RAD51 in Breast Cancer: From Vulnerability to Resistance.

Anjum(RS),Takabe(K) World J Oncol 2026-08-00

...BRCA2)-mutant tumors, impaired RAD51 loading produces profound sensitivity to DNA-damaging agents. However, accumulating...

Lurbinectedin in treating CNS metastases from small cell neuroendocrine prost...

Gunuganti(A),Barve(V),Kelly(WJ),Gunuganti(... Front Oncol None

...BRCA2 and was negative for Rb1 and TP53. He achieved complete systemic response following platinum-based chemoradiothera...

From Diagnosis to Disclosure: Navigating Genetic Counseling Dilemmas in BRCA2...

van Wyk(C),Abdulrahim(R),Crous(I),Al Saegh... Case Rep Genet None

...BRCA2-associated PCa in Omani patients, focusing on family communication, risk awareness, and cascade testing uptake. Th...

A phase 2 multicenter trial of rucaparib and nivolumab as maintenance therapy...

Mohan(A),Griffith(KA),Goff(LW),Crysler(O),... Clin Cancer Res 2026-07-23

...BRCA2 (n = 3), ATM (2), FANCA (1), IDH1 (3)). 4-month PFS rate was 54.8% (95% confidence intervals (CI), 36.0-72.7) in a...

Case Report: Durable complete response to olaparib in a patient with BRCA2-dr...

Karakaya(G) Front Oncol None

...BRCA2 frameshift mutation with somatic loss of heterozygosity. Based on this molecular profile, off-label olaparib thera...

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