...BRCA2 heterozygous deletion), which was controlled by adjuvant radiotherapy combined with nivolumab and nab-paclitaxel, ...
...BRCA2 ) are well known to increase the risk of breast and ovarian cancers. Emerging evidence indicates that BRCA2 mutati...
...BRCA2 alterations have been associated with aggressive disease, the clinical significance of BRCA2 protein expression fo...
...BRCA2, ATM, NF1, and MSH6), and 21 (7.2%) had risk allele variants. One-third (33%) of the disease-causing or likely dis...
...BRCA2 genes. Yet, the role of other cancer susceptibility genes highlights the genetic etiology of HBOC as complex, thus...
...BRCA2)-mutant tumors, impaired RAD51 loading produces profound sensitivity to DNA-damaging agents. However, accumulating...
...BRCA2 and was negative for Rb1 and TP53. He achieved complete systemic response following platinum-based chemoradiothera...
...BRCA2-associated PCa in Omani patients, focusing on family communication, risk awareness, and cascade testing uptake. Th...
...BRCA2 (n = 3), ATM (2), FANCA (1), IDH1 (3)). 4-month PFS rate was 54.8% (95% confidence intervals (CI), 36.0-72.7) in a...
...BRCA2 frameshift mutation with somatic loss of heterozygosity. Based on this molecular profile, off-label olaparib thera...
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