...Brca2 associates with lamin and the cohesion factor Pds5 to secure persistent recombination sites at the nuclear envelop...
To analyze BRCA1 and BRCA2 genes using a cost-effective and rapid approach based on next generation sequencing (NGS) tec...
...BRCA2-containing complex 3 (BRCC3) were identified in 28 cases (1.9%). BRCC3 is a member of the JAMM/MPN+ family of zinc...
...BRCA2 or RAD51C confirmed this prediction in 75% (12/16) of the tested cases. In 14% (6/43) of tumors occurring in BRCA1...
...BRCA2 carriers.,The relative high amount of CNAs in morphologically normal prostate tissue of BRCA2 carriers implies a f...
...BRCA2, CHK1, CHK2, Rad51, ATR) were also observed using real-time RT-PCR. Loss of BRCA1 or BRCA2 gene function has long ...
...BRCA2 founder mutation. None of the alterations were identified in 288 control subjects. Furthermore, we reviewed the 62...
...BRCA2 mutation spectrum in Tunisian young women with breast cancer.,Screening the BRCA2 gene was performed using DHPLC, ...
...BRCA2-deficient ovarian carcinoma cells were hypersensitive toward proton- in comparison with photon-irradiation.,A diff...
...BRCA2 in human cells offers a valuable strategy to disrupt BRCA2 function in cells with intact BRCA2, including tumor ce...
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