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Brca2-Pds5 complexes mobilize persistent meiotic recombination sites to the n...

Kusch(Thomas) J Cell Sci 2016-03-29

...Brca2 associates with lamin and the cohesion factor Pds5 to secure persistent recombination sites at the nuclear envelop...

Two novel frameshift mutations in BRCA2 gene detected by next generation sequ...

Hernan(I),Mañé(B),Borràs(E),de Sousa Dias(... Clin Transl Oncol 2016-04-06

To analyze BRCA1 and BRCA2 genes using a cost-effective and rapid approach based on next generation sequencing (NGS) tec...

BRCC3 mutations in myeloid neoplasms.

Huang(Dayong),Nagata(Yasunobu),Grossmann(V... Haematologica 2016-02-24

...BRCA2-containing complex 3 (BRCC3) were identified in 28 cases (1.9%). BRCC3 is a member of the JAMM/MPN+ family of zinc...

Genomic hallmarks of homologous recombination deficiency in invasive breast c...

Manié(Elodie),Popova(Tatiana),Battistella(... Int J Cancer 2016-05-31

...BRCA2 or RAD51C confirmed this prediction in 75% (12/16) of the tested cases. In 14% (6/43) of tumors occurring in BRCA1...

High burden of copy number alterations and c-MYC amplification in prostate ca...

Castro(E),Jugurnauth-Little(S),Karlsson(Q)... Ann Oncol 2016-08-18

...BRCA2 carriers.,The relative high amount of CNAs in morphologically normal prostate tissue of BRCA2 carriers implies a f...

Effects of aluminium chloride and aluminium chlorohydrate on DNA repair in MC...

Farasani(A),Darbre(P D) J Inorg Biochem 2016-10-11

...BRCA2, CHK1, CHK2, Rad51, ATR) were also observed using real-time RT-PCR. Loss of BRCA1 or BRCA2 gene function has long ...

The role of germline mutations in the BRCA1/2 and mismatch repair genes in me...

Maia(Sofia),Cardoso(Marta),Paulo(Paula),Pi... Fam Cancer 2016-10-05

...BRCA2 founder mutation. None of the alterations were identified in 288 control subjects. Furthermore, we reviewed the 62...

A novel BRCA2 in frame deletion in a Tunisian woman with early onset sporadic...

Hadiji-Abbes(N),Trifa(F),Choura(M),Khabir(... Pathol Biol (Paris) 2016-07-01

...BRCA2 mutation spectrum in Tunisian young women with breast cancer.,Screening the BRCA2 gene was performed using DHPLC, ...

Differential DNA repair pathway choice in cancer cells after proton- and phot...

Fontana(Andrea O),Augsburger(Marc A),Gross... Radiother Oncol 2016-06-10

...BRCA2-deficient ovarian carcinoma cells were hypersensitive toward proton- in comparison with photon-irradiation.,A diff...

Silencing of BRCA2 to Identify Novel BRCA2-regulated Biological Functions in ...

Moro(Loredana),Guaragnella(Nicoletta),Gian... J Vis Exp 2016-03-22

...BRCA2 in human cells offers a valuable strategy to disrupt BRCA2 function in cells with intact BRCA2, including tumor ce...

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