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TP53 BRCA1 CRISPR single-cell cancer

Hamilton(Rebekah J),Innella(Nancy A),Bound... J Genet Couns 2016-09-29

...BRCA2 gene mutation long after the initial diagnosis. These women's experiences across time reflect the concepts of the ...

Giannakeas(Vasily),Sopik(Victoria),Shestop... Gynecol Oncol 2016-02-08

...BRCA2.

Gorodnova(Tatiana V),Sokolenko(Anna P),Iva... Cancer Lett 2016-03-16

...BRCA2 mutation carriers were identified. Complete clinical response was documented in 12/35 (34%) mutation carriers and ...

Biesma(Hedde D),Schouten(Philip C),Lacle(M... Genes Chromosomes Cancer 2016-07-22

...BRCA2-like or non-BRCA-like profiles using previous classifiers derived from FBC, and correlated these profiles with pat...

La Verde(Nicla),Corsi(Fabio),Moretti(Anna)... Tumori 2016-07-11

...BRCA2 mutation. After genetic test results, the available options for treatment/surveillance were discussed by a multidi...

Lin(Y),Wu(Z),Guo(W),Li(J) Tumour Biol 2016-02-02

...BRCA2), chromatin remodeling (ARID1A), cell adhesion (CDH1, FAT4, CTNNA1), cytoskeleton and cell motility (RHOA), Wnt pa...

Adank(Muriel A),Hes(Frederik J),van Zelst-... Ned Tijdschr Geneeskd 2016-04-18

...BRCA2 mutations and the genetic cause of breast cancer remains unexplained. Routine testing for the CHEK2*1100delC mutat...

Weaver(Alice N),Cooper(Tiffiny S),Rodrigue... Oncotarget 2016-08-15

...BRCA2, key factors for non-homologous end joining and homologous recombination respectively. Importantly, the apparent D...

Strom(Charles M),Rivera(Steven),Elzinga(Ch... PLoS One 2016-05-10

The objective of this study was to design and validate a next-generation sequencing assay (NGS) to detect BRCA1 and BRCA...

Münz(Márton),Ruark(Elise),Renwick(Anthony)... Genome Med 2016-05-19

...BRCA2 gene mutations from a clinical pipeline gave 100 % concordance with Sanger data; only 8/25 BRCA2 mutations were co...

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