...BRCA1/2 mutations may be explicable in terms of a polygenic model, with large numbers of susceptibility polymorphisms ac...
...Brca1 C-terminal domain, were at least 10-fold less active in restoring gap filling to the immunodepleted extracts, and ...
Between 5 and 10% of breast cancer is attributable to inherited cancer susceptibility genes. Mutations in the genes BRCA...
...BRCA1 mutation carriers develop hormone-responsive cancer types. Recent studies indicate that BRCA1 interacts with and r...
...BRCA1/2 was also included.,Non-BRCA1/2 infiltrating ductal carcinomas (IDCs) showed specific differences from BRCA1 tumo...
...BRCA1 proteins from several species. We found that full-length BRCA1 proteins universally fail to activate transcription...
...BRCA1, a tumor suppressor gene that has an important role in breast and ovarian cancer. The expression of STC2 is induce...
...BRCA1 are critical for genome stability at fragile sites have shed new light on these mechanisms and on the biological s...
Because inherited BRCA1 or BRCA2 mutations strikingly increase ovarian cancer risk, polymorphisms in these genes could r...
...BRCA1 locus. Twenty-Two lymphoblastoid cell line DNA samples with an initial concentration of approximately 350 ng/uL we...
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