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Molecular landscape of prostate cancer: implications for current clinical tri...

Khemlina(Galina),Ikeda(Sadakatsu),Kurzrock... Cancer Treat Rev 2016-01-26

...BRCA2 and ATM, are present in both somatic and germline form in a significant minority of prostate cancer; these abnorma...

Outcome of neoadjuvant chemotherapy in BRCA1/2 mutation positive women with a...

Mahdi(Haider),Gockley(Allison),Esselen(Kat... Gynecol Oncol 2016-04-12

...BRCA2 mutation had non-significant trend toward longer PFS compared to patients with unknown BRCA or BRCA1 mutation (20....

Comprehensive spectrum of BRCA1 and BRCA2 deleterious mutations in breast can...

Kwong(Ava),Shin(Vivian Y),Ho(John C W),Kan... J Med Genet 2016-10-12

...BRCA2 mutations. Some mutations are unique to one family and others are recurrent; the spectrum of BRCA1/BRCA2 mutations...

FANCD2 and REV1 cooperate in the protection of nascent DNA strands in respons...

Yang(Yeran),Liu(Zhenbo),Wang(Fengli),Temvi... Nucleic Acids Res 2016-01-11

...BRCA2, components of the FANCD2/BRCA supercomplex. Intriguingly, analogous to FANCD2-mUb and BRCA1/BRCA2, REV1 plays an ...

Spectrum and frequencies of BRCA1/2 mutations in Bulgarian high risk breast c...

Dodova(Rumyana Ivanova),Mitkova(Atanaska V... BMC Cancer 2016-04-28

...BRCA2 c.9098-9099insA (2 %), BRCA1 c.181T > G (1 %) and BRCA2 c.5851_5854delAGTT (1 %). Notably, BRCA1 c.5263_5264insC r...

Preemptive Bone Marrow Transplantation for FANCD1/BRCA2.

Khan(Nicholas E),Rosenberg(Philip S),Lehma... Biol Blood Marrow Transplan... 2016-06-23

...BRCA2 are at uniquely high risks of leukemia and solid tumors. Preemptive bone marrow transplantation (PE-BMT) has been ...

Effect of Oophorectomy on Survival After Breast Cancer in BRCA1 and BRCA2 Mut...

Metcalfe(Kelly),Lynch(Henry T),Foulkes(Wil... JAMA Oncol 2016-03-29

Women who carry a germline mutation in either the BRCA1 or BRCA2 gene face a lifetime risk of breast cancer of up to 70%...

Association of Somatic Mutations of ADAMTS Genes With Chemotherapy Sensitivit...

Liu(Yuexin),Yasukawa(Maya),Chen(Kexin),Hu(... JAMA Oncol 2016-04-04

...BRCA2 mutation, surgical stage, residual tumor, and patient age, ADAMTS mutations were significantly associated with bet...

A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage ...

Scarbrough(Peter M),Weber(Rachel Palmieri)... Cancer Epidemiol Biomarkers... 2016-10-25

...BRCA2 (P = 5.70 × 10(-6)). Hierarchical modeling identified several pleiotropic associations with cancer risk in the bas...

The rate of recurrent BRCA1, BRCA2, and TP53 mutations in the general populat...

Schayek(Hagit),De Marco(Luiz),Starinsky-El... Cancer Genet 2016-06-23

...BRCA2 (c.5946delT, c.8537_8538delAG, 4936_4939delGAAA), the c.156_157insAlu* BRCA2 and the c.1010G>A *TP53 mutation were...

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