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TP53 BRCA1 CRISPR single-cell cancer

Vos(Janet R),Mourits(Marian J),Teixeira(Na... Gynecol Oncol 2016-06-01

...BRCA2 carriers in the 1935-1953 cohort had an HRadjusted of 3.01 (95% CI 1.47-6.13). The SIRs for the 1935-1953 and post...

Kuznia(Angela L),Roett(Michelle A) FP Essent 2016-02-02

...BRCA2 gene mutations (40% and 18% risk, respectively, by age 70 years) or hereditary nonpolyposis colorectal cancer synd...

Kondrashova(Olga),Love(Clare J),Lunke(Seba... PLoS One 2016-06-20

...BRCA2, ERBB2 and CCNE1 copy number changes in DNA extracted from snap-frozen and FFPE tumour tissue, with 100% sensitivi...

Martinez(Juan S),Baldeyron(Céline),Carreir... Cell Cycle 2016-08-29

...BRCA2 remains undetermined, and the heterogeneity of BRCA2-associated tumors challenges the identification of causative ...

Bhatla(Teena),Dandekar(Smita),Lu(Benjamin ... J Pediatr Hematol Oncol 2016-05-06

...BRCA2 with LOH at that same position in the tumor tissue was also found. Our data provide valuable insight into the geno...

Churpek(Jane E),Marquez(Rafael),Neistadt(B... Cancer 2016-05-13

...BRCA2 (2 subjects; 4%), TP53 (tumor protein p53) (3 subjects; 6%), CHEK2 (checkpoint kinase 2) (1 subject; 2%), and PALB...

Navrátil(J),Fabian(P),Palácová(M),Petrákov... Klin Onkol 2016-02-11

...BRCA2.,The objective of this review is to provide comprehensive information about current knowledge of triple negative b...

Petráková(K),Palácová(M),Schneiderová(M),S... Klin Onkol 2016-03-07

...BRCA2 carriers from the age of 40 onwards and it should be considered in BRCA1 carriers as well. Screening for melanoma ...

Zikán(M) Klin Onkol 2016-03-07

...BRCA2 mutation carriers, and proposes guidelines for furher management of these women, addressing follow-up recommendati...

Janatová(M),Borecká(M),Soukupová(J),Kleibl... Klin Onkol 2016-03-07

The PALB2 (FANCN) gene was identified as a component of endogenous BRCA2 complex that encodes a DNA repair protein parti...

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