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Xing(B),Zhang(X),Zhu(H),Gu(X) Int J Surg Pathol 2026-04-23

...BRCA2 variant of uncertain significance (Class III) in a tunica vaginalis micropapillary serous borderline tumor with mi...

Armon(S),Lieberman(S),Michaelson-Cohen(R),... JCO Precis Oncol 2026-04-00

...BRCA2-PVs (62.9% v 48.7%, P = .001) rather than BRCA1-PVs, and fewer had suggestive family history (FH) (40.4% v 61%, P ...

Blanc-Durand(F),Yaniz Galende(E),Ferron(G)... NPJ Genom Med 2026-04-23

...BRCA2 mutations and BRCA1 and RAD51C promoter methylation, and a strong association between RB1 loss co-occurring with a...

Chailapakul(P),Maeda(J),Miura(T),Kato(TA) Mutagenesis 2026-08-27

...BRCA2 mutant line, V-C8. Using CRISPR/Cas9 editing, we generated a hypomorphic BRCA1 mutant, designated B1-21, carrying ...

Abe(M),Saito(F),Honma(N),Tamaki(Y),Goto(M)... Case Rep Pathol None

...BRCA2 gene mutation (c.331_347delinsC [p.Asn111Leufs∗5]). Simultaneous surgery was performed for bilateral breast cancer...

Park(S),Cao(E),Amar(S) Cureus 2026-01-00

...BRCA2 mutations and gastric cancer (GC) remains understudied. This case involves a patient with a pathogenic BRCA2 mutat...

Leonard(SM),Pearson(CR),Roos(WP),Sobol(RW) Toxics 2026-02-10

...BRCA2 mutant tumors. USP1 is a deubiquitylating enzyme responsible for the removal of the mono-ubiquitin mark on FANCD2,...

Jani(CT),Tran(E),Zhang(N),Tsai(J),Dong(J),... Clin Cancer Res 2026-05-15

...BRCA2 (22.9%/17%), BRCA1 (4%/2.1%), and CDK12 (5.9%/5.9%). After taxane, frequent alterations included TP53 (47.2%→54%),...

Ammous-Boukhris(N),Abdelmaksoud-Dammak(R),... Mol Biol Rep 2026-02-26

BACKGROUND: Pathogenic variants in BRCA1 and BRCA2 are well known drivers of homologous recombination deficiency in ovar...

Dutta(S),Rashid(SMM),Islam(S),Ahmed(SF),Ay... Cancer Inform None

...BRCA2. Comprehensive sequencing of the full lengths of BRCA1 and BRCA2 may be necessary to ensure confident clinical int...