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TP53 BRCA1 CRISPR single-cell cancer

de la Hoya(Miguel),Sulleiro(Sara),Osorio(A... Int J Cancer 2002-08-16

...BRCA1-positive families, we find that most (11 of 15 different mutations) BRCA1 defects are linked to chromosomes with s...

Metcalfe(Kelly A),Goel(Vivek),Lickley(Lavi... Cancer 2002-08-08

...BRCA1 or BRCA2 mutation (10 of 99). Twenty percent of the women had no family history, but had the surgery for other ben...

Jara(Lilian),Ampuero(Sandra),Seccia(Lorena... Biol Res 2002-09-04

...BRCA1 and BRCA2 are the two main hereditary breast cancer susceptibility genes, and mutations in these genes are related...

Derbyshire(Dean J),Basu(Balaku P),Serpell(... EMBO J 2002-09-05

The BRCT (BRCA1 C-terminus) is an evolutionary conserved protein-protein interacting module found as single, tandem or m...

Zhong(Qing),Boyer(Thomas G),Chen(Phang-Lan... Cancer Res 2002-08-13

BRCA1 ensures genomic stability, at least in part, through a functional role in DNA damage repair. BRCA1 interacts with ...

Turner(Bruce C),Ottey(Michelle),Zimonjic(D... Cancer Res 2002-08-13

...BRCA1 cancers compared with sporadic breast tumors (9% Fhit positive versus 68% Fhit positive), suggesting that the BRCA...

Chan(Kelvin Y K),Ozçelik(Hilmi),Cheung(Ann... Cancer Res 2002-08-13

...BRCA1 promoter highly correlated with decreased BRCA1 expression (P = 0.017). Methylated CpGs at the BRCA2 promoter were...

Peto(Julian) Cancer Cell 2002-09-27

...BRCA1 and BRCA2.

Pace(Paul),Johnson(Mark),Tan(Wu Meng),Mose... EMBO J 2002-08-15

...BRCA1 protein at sites of DNA damage. Here we show that the recently identified FANCE protein is part of this nuclear co...

Contant(C M E),Menke-Pluijmers(M B E),Seyn... Eur J Surg Oncol 2002-11-08

...BRCA1 or BRCA2 germ-line mutation or with a 50% risk of carrying the mutation, have an increased risk of breast cancer. ...

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