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Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-...

Kang(Xiaozheng),Liu(Hongliang),Onaitis(Mar... Carcinogenesis 2016-08-10

...BRCA2). After combined the results from TRICL with those from Harvard and deCODE, the most significant association (P co...

Multiplexed pancreatic genome engineering and cancer induction by transfectio...

Maresch(Roman),Mueller(Sebastian),Veltkamp... Nat Commun 2016-07-12

...Brca2-inactivation in a Kras-mutant context. We also demonstrate modelling of chromosomal deletions and targeted somatic...

Medical implications of technical accuracy in genome sequencing.

Goldfeder(Rachel L),Priest(James R),Zook(J... Genome Med 2016-10-13

...BRCA2.,Together, these data illustrate the importance of appropriate use and continued improvement of technical benchmar...

Prophylactic salpingo-oophorectomy in BRCA1 mutation carriers and postoperati...

Menkiszak(Janusz),Chudecka-Głaz(Anita),Gro... J Ovarian Res 2016-10-11

...BRCA2 carriers.,One hundred ninety-five patients, carriers of one of three most common mutations of the BRCA1 gene (Am J...

Panel Testing for Familial Breast Cancer: Calibrating the Tension Between Res...

Thompson(Ella R),Rowley(Simone M),Li(Na),M... J Clin Oncol 2016-11-10

...BRCA2 wild type. Controls (n = 1,997) were cancer-free women from the LifePool study. Sequencing data were filtered for ...

BRCA testing, treatment patterns and survival in platinum-sensitive recurrent...

Unni(Sudhir K),Schauerhamer(Marisa B),Deka... J Ovarian Res 2016-10-11

...BRCA2 (BRCAm) result in loss of these repair mechanisms and potential carcinogenesis. Germline BRCAm are common in ovari...

Frequency and Significance of Abnormal Pancreatic Imaging in Patients with BR...

Chahla(Elie),Cheesman(Antonio),Mahon(Suzan... Scientifica (Cairo) 2016-04-12

...BRCA2 mutation carriers. Methods. A retrospective review of patient medical records with known BRCA1 and BRCA2 mutations...

The genetic prediction of risk for gynecologic cancers.

Randall(Leslie M),Pothuri(Bhavana) Gynecol Oncol 2016-08-16

...BRCA2, and DNA mismatch repair genes: MLH1, MSH2, MSH6, and PMS2 are important causal agents in hereditary breast and ov...

Decreased Expression of BRCA2 Accelerates Sporadic Breast Cancer Progression.

Saha(Soumi),Mandal(Pranab),Ganguly(Suvro),... Indian J Surg Oncol 2016-04-12

...BRCA2 expression. In patients with higher grade of tumors the level of BRCA2 expression was found to be low. Decreased e...

Identifying Women at Risk for Hereditary Breast and Ovarian Cancer Syndrome U...

Appel(Susan J),Cleiment(Rosemary J) J Natl Black Nurses Assoc 2016-05-16

...BRCA2, account for the majority of these hereditary related breast cancers. Additionally, BRCA1 and BRCA2 are related to...

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