The purpose of this study was to evaluate risk-reducing mastectomy (RRM) uptake in older BRCA1/2 and PALB2 carriers who ...
...BRCA1 (24.4% vs 0.4%) (Pvalues < .001 for all). The LRR-PCa cohort had a significantly higher Decipher score (median, 0....
...BRCA1 mutation and exploratory laparotomy with pancreatoduodenectomy who underwent risk-reducing laparoscopic bilateral ...
...BRCA1-associated protein-1 (BAP1), have been recognized as common in ccRCC. Although these genomic alterations are centr...
...BRCA1 binding sites (BBS) were identified within this promoter region. Subsequent experimental results suggest that BRCA...
...BRCA1 and BRCA2, represents a critical tool for precision oncology, enabling individualized risk stratification and the ...
...BRCA1, TOP2A, BRCA2, BUB1B, HSP90AA1, PLK4, and EDIL3), with EDIL3 showing the greatest increase in BA. EDIL3 is located...
...BRCA1-associated SGTs. We report a Colombian family segregating the BRCA1 c.3331_3334delCAAG (p.Gln1111Asnfs*5) founder ...
...BRCA1/2, TP53, PTEN, CHEK2, PALB2, and others) was negative, excluding hereditary predisposition. Tumor profiling confir...
...BRCA1, DNMT1, EZH2, PTTG1, SND1, UHRF1). APEX1 was downregulated in CRC, while the other six were upregulated. The diagn...
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