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Whole-Exome Sequencing: Discovering Genetic Causes of Granulomatous Mastitis.

Ozcinar(B),Ocak(Z),Billur(D),Ertugrul(B),Tim… Int J Mol Sci 2025-01-06

...BRCA2 (rs169547), CFTR (rs4727853), NCF1 (rs10614), PTPN22 (rs2476601), HLA-DRB1 (seven variants), and C3 (rs406514). No...

Association between homologous recombination repair gene mutations and response…

Kondo(T),Kanai(M),Kou(T),Sakuma(T),Mochizuki… Oncotarget 2018-04-13

...BRCA2, BLM, CHEK1, CHEK2, FANCA, MRE11A, PALB2, and RAD51) were sequenced using a Clinical Laboratory Improvement Amendm...

Genetic advancements in breast cancer treatment: a review.

Shokoohi(M),Sedaghatshoar(S),Arian(H),Mokara… Discov Oncol 2025-02-07

...BRCA2, allowing for more tailored and effective interventions. As research progresses, the constructive interaction betw...

Involvement and Influence of Healthcare Providers, Family Members, and Other Mu…

Puski(A),Hovick(S),Senter(L),Toland(AE) J Genet Couns 2018-00-00

Deciding between increased cancer screening or prophylactic surgery and the timing of such procedures can be a difficult...

Loss of Brcc3 in Zebrafish Embryos Increases Their Susceptibility to DNA Damage…

Wang(Z),Wang(C),Zhai(Y),Bai(Y),Wang(H),Rong(… Int J Mol Sci 2024-11-11

...BRCA2-containing complex subunit 3 (BRCC3), also known as BRCC36, functions within various multiprotein complexes to med...

Unveiling the molecular profile of a prostate carcinoma: implications for perso…

Agostini(M),Giacobbi(E),Servadei(F),Bishof(J… Biol Direct 2024-12-31

...BRCA2 genes play a key role in the pathogenesis of prostate cancer, specific gene alteration signature that could distin...

Combined annotation-dependent depletion score for BRCA1/2 variants in patients …

Nakagomi(H),Mochizuki(H),Inoue(M),Hirotsu(Y)… Cancer Sci 2018-02-00

...BRCA2. All deleterious mutations were included in this group. Frequency of personal history and family history of ovaria...

The NHS England Jewish BRCA Testing Programme: overview after first year of imp…

Torr(B),Bell(N),McCarthy(R),Hamill(M),Nolan(… J Med Genet 2025-01-27

...BRCA2 genetic testing to people with ≥1 Jewish grandparent. Who have an increased likelihood of having an Ashkenazi Jewi...

Simultaneous detection of genetic and copy number alterations in BRCA1/2 genes.

Hirotsu(Y),Ooka(Y),Sakamoto(I),Nakagomi(H),O… Oncotarget 2017-12-29

...BRCA2 genes (BRCA1/2) predispose to hereditary breast and ovarian cancer syndrome (HBOC), and their dysregulation increa...

[Early Recurrence of Triple Negative Breast Cancer with Pathological Complete R…

Yanagawa(N),Sugimoto(T),Oki(T),Fukunaga(Y),O… Gan To Kagaku Ryoho 2024-12-00

...BRCA2 variant, a risk-reducing salpingo-oophorectomy was scheduled. However, liver metastases were detected on a preoper...

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