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Germline Pathogenic Variants in Patients with Pancreatic Ductal Adenocarcinoma …

Kryklyva(V),Pflüger(MJ),Ouchene(H),Volleberg… Mod Pathol 2025-05-00

...BRCA2 (n = 10), or CHEK2 (n = 10) genes. The combination of PDAC and ovarian carcinoma carried the highest prevalence of...

Prevalence of BRCA mutations among hereditary breast and/or ovarian cancer pati…

Abdulrashid(K),AlHussaini(N),Ahmed(W),Thalib… BMC Cancer 2019-03-21

...BRCA2 gene mutations in women with Hereditary Breast and/or Ovarian Cancer (HBOC) in Arab countries and to describe the ...

BRCA-CN: a blockchain-based framework to support public variant databases shari…

Qu(S),Liu(R),Li(S),Huang(C),Zhang(Y),Gao(X),… Hum Genet 2025-08-00

...BRCA2: 585), completing consensus reviews for 607 sites with 462 achieving definitive interpretations. Comparison with C...

Germline Genetic Testing: What the Breast Surgeon Needs to Know.

Plichta(JK),Sebastian(ML),Smith(LA),Menendez… Ann Surg Oncol 2019-07-00

...BRCA2, and other breast cancer genes that markedly increase their risk of developing breast cancer. As genetic testing i...

International trends in the uptake of cancer risk reduction strategies in women…

Metcalfe(K),Eisen(A),Senter(L),Armel(S),Bord… Br J Cancer 2019-00-00

...BRCA2 mutation face high risks of breast and ovarian cancer. In the current study, we report on uptake of cancer screeni...

Variant classification changes over time in BRCA1 and BRCA2.

Mighton(C),Charames(GS),Wang(M),Zakoor(KR),W… Genet Med 2019-00-00

...BRCA2 (BRCA1/2) variant reassessments and reclassifications between 2012 and 2017 at the Advanced Molecular Diagnostics ...

Direct Genetics Referral Pathway for High-Grade Serous Ovarian Cancer Patients:…

McGee(J),Peart(TM),Foley(N),Bertrand(M),Pref… J Oncol 2019-00-00

...BRCA2 gene mutation. Of the women who tested positive for a BRCA1/2 mutation, 56% had no family history of breast or ova...

Homologous Recombination in Thyroid Tumor Samples.

Spirina(LV),Tsyganov(MM),Chizhevskaya(SY),Ta… Int J Mol Sci 2025-10-06

...BRCA2, and FANCA genes, typically associated with thyroid tumors, were identified in the tissue of papillary thyroid can...

Uptake of genetic testing for germline BRCA1/2 pathogenic variants in a predomi…

McGuinness(JE),Trivedi(MS),Silverman(T),Mart… Cancer Genet 2019-00-00

...BRCA2 (BRCA1/2) testing, particularly among racial/ethnic minorities. We evaluated the uptake of BRCA1/2 genetic testing...

The Evolving Landscape of Chemotherapy in Newly Diagnosed Advanced Epithelial O…

Monk(BJ),Randall(LM),Grisham(RN) Am Soc Clin Oncol Educ Book 2019-01-00

...BRCA2 mutation. This was based on the results of SOLO-1. Despite a strong rationale and extensive study, intraperitoneal...

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