...BRCA2, RPA1, and Rad51, were detected both in FaDu-RR cells and radioresistant xenograft. We established the specificall...
...BRCA2 (BRCA). Challenging this assumption are recent findings that indicate chemotherapies, such as cisplatin used to tr...
...BRCA2 (4%), ATR (3%), RAD50 (3%) and BRIP1 (3%) were the most frequently mutated. In the MSK-IMPACT COAD cohort (immune ...
...BRCA2, FANCA, FANCD2, MLH1, MSH2, MSH6, PALB2, POLD1, POLE, PRKDC, and RAD50) and caretaker genes (BAP1, CDK12, MLL3, TP...
...BRCA2, VUS in TP53, and VUS in NFU1 were detected. Exome sequencing further identified genetic alterations by 5.6% in pr...
...BRCA2) candidate neoantigen-encoding genes were selected as diagnostic signatures. They respectively showed 100% and 97%...
...BRCA2, PALB2, ATM, and CHEK2-are frequently associated with hereditary breast and ovarian cancer syndrome. Germline muta...
...BRCA2 mutated breast and ovarian cancers but resistance to PARPi is common. Published results found that resistance to O...
...BRCA2, CHEK2) occurred in 5.1% of the unselected series, with unclear significance for RCC. Our findings confirm a high ...
...BRCA2 (6, 1.1%), while 19 patients (3.5%) were heterozygotes for MUTYH P/LPVs and 9 (1.6%) carried the low-risk allele, ...
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