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Price(R Jordan),Lillycrop(Karen A),Burdge(... Nutr Res 2016-03-01

...BRCA2. FA treatment induced dose-related increases in BRCA1 mRNA expression in HepG2, Huh-7D12, Hs578T, and JURKAT and i...

Holter(Spring),Borgida(Ayelet),Dodd(Anna),... J Clin Oncol 2016-01-08

The main purpose of this study was to determine the prevalence of pathogenic BRCA1 and BRCA2 mutations in a consecutivel...

Verhagen(Caroline V M),de Haan(Rosemarie),... Radiother Oncol 2016-06-10

...BRCA2-deficient and BRCA2-complemented cells and in a panel of human head and neck squamous cell carcinoma cell lines.,T...

Menes(Tehillah S),Terry(Mary Beth),Goldgar... Breast Cancer Res Treat 2016-02-24

BReast CAncer genes 1 and 2 (BRCA1 and BRCA2) mutation carriers diagnosed with breast cancer are at increased risk of de...

Arun(Banu),Akar(Ugur),Gutierrez-Barrera(An... Int J Oncol 2016-03-21

...BRCA2 genes. In this study, we investigated the antiproliferative effects and mechanism of PARP inhibitors ABT-888 (Veli...

Talukder(Asoke K),Ravishankar(Shashidhar),... PLoS One 2016-01-19

...BRCA2 breast cancer exome data. The results showed that the most significantly affected pathways across all samples are ...

Bonsignore(Lindsay A),Butler(Jill Sergeske... Oncotarget 2016-04-05

...BRCA2, its loss may result in tumors with enhanced sensitivity to diverse DNA damaging chemotherapeutics.

Srinivas(Upadhyayula Sai),Dyczkowski(Jerzy... Oncotarget 2016-03-25

...BRCA2, were found upregulated in CRC biopsies as compared to normal mucosa. Inhibition of HR by targeting Rad51 enhanced...

Muendlein(Axel),Rohde(Bettina H),Gasser(Kl... J Cancer Res Clin Oncol 2016-05-02

Testing for BRCA1 and BRCA2 mutations in breast cancer patients is used to identify the risk of second primary cancers a...

Movva(Sujana),Wen(Wenhsiang),Chen(Wangjuh)... Oncotarget 2016-04-05

...BRCA2 (17.6%). Overexpression of TOPO2A was associated with TP53 mutation (P = 0.0001).,This data provides the landscape...