...BRCA2. In addition, 414, 734, 449, and 307 variants were also recorded in the BIC, ClinVar, ENIGMA, and UMD databases, r...
...BRCA2 exon 12 (E12) as a model system because its in-frame skipping leads to a potentially functional protein. All E12 v...
...BRCA2 mutation showed increased sensitivity in irinotecan. In conclusion, the carryover effects of olaparib to improve a...
...BRCA2 mutations is around 80%. Genetically engineered BRCA1-deficient mouse models offer a unique opportunity to study t...
...BRCA2 hereditary breast and ovarian cancer syndromes, many other syndromes that are associated with genetic mutations pr...
...BRCA2, respond favorably to PARP inhibition and platinum-based chemotherapy. We investigated whether other prostate tumo...
...BRCA2, PALB2, PTCH1, SUFU, TP53, and GPR161. The strongest evidence for association was found for rs201458864 (PALB2, OR...
...BRCA2 (n = 800). Given the increasing number of childhood cancer survivors in the United States, clinicians should couns...
...BRCA2 mutations. Four histologic subtypes characterized by different mutations have been described: serous, endometrioid...
...BRCA2 were sensitive to 5-FU in the presence of ATR inhibitor. Moreover, ATR inhibition enhanced the efficacy of the 5-F...
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