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Attendance of men at the familial cancer clinic: what they value from the consu…

Lobb(EA),Gaff(CL),Meiser(B),Butow(PN),Osseir… Genet Med 2009-06-00

...BRCA2 mutation completed a self-administered questionnaire. Seventy- two percent (72%) of men attended the familial canc...

Role of genetic polymorphisms and ovarian cancer susceptibility.

Fasching(PA),Gayther(S),Pearce(L),Schildkrau… Mol Oncol 2009-04-00

...BRCA2 genes. Women who inherit a deleterious mutation in either of these genes have a very high lifetime risk of ovarian...

Breast cancer and ovarian cancer genetics: an update.

Edlich(RF),Cross(CL),Wack(CA),Chase(ME),Lin(… J Environ Pathol Toxicol Oncol 2008-00-00

...BRCA2 carriers. This collective review highlights radiologic screening of patients with this genetic predisposition for ...

Cancer control in susceptible groups: opportunities and challenges.

Li(FP) J Clin Oncol 1999-02-00

...BRCA2, markedly increase the risk of cancers at unusually early ages. Increasing numbers of these highly penetrant genes...

Expressed sequences as candidates for a novel tumor suppressor gene at band 13q…

Stilgenbauer(S),Nickolenko(J),Wilhelm(J),Wol… Oncogene 1998-04-09

...BRCA2 gene at band 13q12 was found. Detailed deletion mapping at band 13q14 with probes from the RB1-D13S25 interval lea...

Substrate specificities and identification of putative substrates of ATM kinase…

Kim(ST),Lim(DS),Canman(CE),Kastan(MB) J Biol Chem 1999-12-31

...Brca2, phosphatidylinositol 3-kinase, and DNA-5B peptides were phosphorylated specifically by ATR, and DNA Ligase IV is ...

Mutation and expression analysis of human BUB1 and BUB1B in aneuploid breast ca…

Myrie(KA),Percy(MJ),Azim(JN),Neeley(CK),Pett… Cancer Lett 2000-05-01

...Brca2 deficient murine cells, Bub1 mutants potentiate growth and cellular transformation. This would suggest that aneupl...

Behavioral risk factors among women presenting for genetic testing.

Emmons(KM),Kalkbrenner(KJ),Klar(N),Light(T),… Cancer Epidemiol Biomarkers P… 2000-01-00

...BRCA2). Before participation in a genetic testing program, 119 women completed a series of questionnaires designed to as...

Genetic susceptibility testing and prophylactic oophorectomy.

Berchuck(A),Carney(ME),Futreal(PA) Eur J Obstet Gynecol Reprod B… 1999-02-00

...BRCA2), oophorectomy can now be offered specifically to women who are mutation carriers. Conversely, non-carriers in the...

Identification of a 3 kb Alu-mediated BRCA1 gene rearrangement in two breast/ov…

Montagna(M),Santacatterina(M),Torri(A),Menin… Oncogene 1999-07-15

...BRCA2 genes; nonetheless, germline mutations of these genes in 'high risk' families are found less frequently than expec...

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