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Analysis of albumin-associated peptides and proteins from ovarian cancer patien…

Lowenthal(Mark S),Mehta(Arpita I),Frogale(Kr… Clin Chem 2006-01-11

...BRCA2, a 390-kDa low-abundance nuclear protein linked to cancer susceptibility, was represented in sera as a series of s...

Communication and decision-making about seeking inherited cancer risk informati…

Mellon(Suzanne),Berry-Bobovski(Lisa),Gold(Ro… Psychooncology 2006-08-10

...BRCA2 have led to new options in genetic risk assessment for families with histories of breast and ovarian cancer. Howev...

Solution structure of the human ubiquitin-specific protease 15 DUSP domain.

de Jong(Rob N),Ab(Eiso),Diercks(Tammo),Truff… J Biol Chem 2006-05-04

...BRCA2. We describe the NMR solution structure of the DUSP domain of human USP15, recently implicated in COP9 (constituti...

Age of uptake of early cancer detection facilities by low-risk and high-risk pa…

Lux(Michael Patrick),Ackermann(Sven),Bani(Ma… Eur J Cancer Prev 2006-02-28

...BRCA2 genes, as well as 205 who did not meet these criteria but attended the primary consultation.,Consulters who met th...

BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma c…

Pal(Tuya),Permuth-Wey(Jenny),Betts(Judith A)… Cancer 2006-01-19

...BRCA2, including 20 BRCA1 mutations and 12 BRCA2 mutations. Of the BRCA2 mutations, 58% were outside the "ovarian cancer...

Hereditary breast and ovarian cancer: review and future perspectives.

Lux(Michael P),Fasching(Peter A),Beckmann(Ma… J Mol Med (Berl) 2006-12-11

...BRCA2 mutations are responsible for 3-8% of all cases of BC and 30-40% of familial cases. Ten percent of patients with O...

Patterns of reduced nipple aspirate fluid production and ductal lavage cellular…

Higgins(Susan A),Matloff(Ellen T),Rimm(David… Breast Cancer Res 2006-02-27

...BRCA2 germline mutation) to identify ductal orifices for lavage procedures. Lavage was performed on all fluid-yielding d...

A common missense variant in BRCA2 predisposes to early onset breast cancer.

Górski(Bohdan),Narod(Steven A),Lubinski(Jan) Breast Cancer Res 2006-02-27

...BRCA2 gene are one of the two major causes of hereditary breast cancer. Protein-truncating mutations of BRCA2 are usuall...

In vivo therapeutic responses contingent on Fanconi anemia/BRCA2 status of the …

van der Heijden(Michiel S),Brody(Jonathan R)… Clin Cancer Res 2006-02-13

BRCA2, FANCC, and FANCG gene mutations are present in a subset of pancreatic cancer. Defects in these genes could lead t...

Prophylactic mastectomy: why and when?

von Smitten(Karl) J Br Menopause Soc 2006-07-18

Introduction of BRCA1 and BRCA2 gene mutation analysis has increased interest in prophylactic mastectomy and immediate b...

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