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Application of BRCA1 and BRCA2 mutation carrier prediction models in breast and…

Oros(K K),Ghadirian(P),Maugard(C M),Perret(C… Clin Genet 2006-11-28

...BRCA2 mutation carrier status of women at high risk for developing the heritable form of breast and ovarian cancers. We ...

Low rates of acceptance of BRCA1 and BRCA2 test results among African American …

Halbert(Chanita Hughes),Kessler(Lisa),Stopfe… Genet Med 2006-11-08

...BRCA2 (BRCA1/2) test result acceptance among African American women and identified determinants of test result acceptanc...

[The limited spectrum of pathogenic BRCA1 and BRCA2 mutations in the French Can…

Tonin(Patricia N) Bull Cancer 2006-09-27

...BRCA2, the breast-ovarian cancer susceptibility genes. Here we review BRCA1 and BRCA2 in the context of French Canadian ...

Identification of BRCA1 and BRCA2 mutations from Korean breast cancer patients …

Kim(Bo-Young),Lee(Dong-Geun),Lee(Kyoung-Ryul… Biochem Biophys Res Commun 2006-10-30

...BRCA2 mutations. We found that BRCA deleterious mutations were present in 19 of the 1020 patients (1.8%). Three of the 1...

Gene x Gene interaction between MnSOD and GPX-1 and breast cancer risk: a neste…

Cox(David G),Tamimi(Rulla M),Hunter(David J) BMC Cancer 2006-11-08

...BRCA2, and ATM can cause a substantial increase in risk of breast cancer. However, these mutations are rare in the gener...

Prophylactic bilateral salpingo-oophorectomy compared with surveillance in wome…

Schmeler(Kathleen M),Sun(Charlotte C),Bodurk… Obstet Gynecol 2006-10-04

...BRCA2 mutation.,Between 1996 and 2005, 139 women who tested positive for a BRCA1 or BRCA2 mutation were identified. Thir...

Mechanism of homologous recombination: mediators and helicases take on regulato…

Sung(Patrick),Klein(Hannah) Nat Rev Mol Cell Biol 2006-11-06

...BRCA2, which has a mediator function in HR, lead to cancer formation. DNA helicases, such as Bloom's syndrome protein (B...

Optimal selection for BRCA1 and BRCA2 mutation testing using a combination of '…

Bodmer(D),Ligtenberg(M J L),van der Hout(A H… Br J Cancer 2006-12-04

...BRCA2 can be optimised by using a combination of available easy to apply risk assessment models.

A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated…

Shivji(Mahmud K K),Davies(Owen R),Savill(Jan… Nucleic Acids Res 2006-09-13

...BRCA2 might fulfill these dual functions is unclear. We have purified a fragment of human BRCA2 (BRCA2(BRC1-8)) with 112...

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