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A novel human rad54 homologue, Rad54B, associates with Rad51.

Tanaka(K),Hiramoto(T),Fukuda(T),Miyagawa(K... J Biol Chem 2000-09-25

...BRCA1. These findings suggest that Rad54B may be functionally distinct from Rad54, although it may play an active role i...

Acceleration of chromosomal instability by loss of BRCA1 expression and p53 a...

Miyoshi(Y),Iwao(K),Takahashi(Y),Egawa(C),N... Cancer Lett 2000-11-21

...BRCA1 negative/p53 normal tumors (28.9+/-13.8, n=23) and those of BRCA1 positive/p53 abnormal tumors (27.0+/-2.3, n=3) w...

BRCA1 and BRCA2--breast cancer susceptibility genes.

Hofmann(W),Schlag(P M) J Cancer Res Clin Oncol 2000-09-27

...BRCA1 (breast cancer gene 1) and BRCA2 and the current genetic testing for mutations in both genes are the basis for est...

Tumor suppressor p53 is required to modulate BRCA1 expression.

Arizti(P),Fang(L),Park(I),Yin(Y),Solomon(E... Mol Cell Biol 2000-10-30

...BRCA1 genes. Here we show that BRCA1 expression levels are down-regulated in response to p53 induction in cells that und...

Regulation of the insulin-like growth factor-I receptor gene by oncogenes and...

Werner(H),Shalita-Chesner(M),Abramovitch(S... Mol Genet Metab 2000-11-13

...BRCA1. It has been demonstrated that, in their wild-type form, these transcription factors can suppress the activity of ...

Histology of prophylactically removed ovaries from BRCA1 and BRCA2 mutation c...

Casey(M J),Bewtra(C),Hoehne(L L),Tatpati(A... Gynecol Oncol 2000-09-25

...BRCA1 and BRCA2 mutation status had been tested were selected from our database. Thirty had tested positive for BRCA1 mu...

Rapid detection of deletion, insertion, and substitution mutations via hetero...

Tian(H),Brody(L C),Landers(J P) Genome Res 2000-10-17

...BRCA1, and 6174delT in BRCA2. For this system, the effective fragment size for CE-based HDA was found in the range of 20...

BRCA1 physically and functionally interacts with ATF1.

Houvras(Y),Benezra(M),Zhang(H),Manfredi(J ... J Biol Chem 2000-12-29

...BRCA1 contains an N-terminal RING finger that mediates protein-protein interaction. The C-terminal domain of BRCA1 (BRCT...

The rate of the founder Jewish mutations in BRCA1 and BRCA2 in prostate cance...

Vazina(A),Baniel(J),Yaacobi(Y),Shtriker(A)... Br J Cancer 2000-08-22

...BRCA1) and 6174delT (BRCA2) occur in about 2.5% of the general Ashkenazi population, and the 185delAG BRCA1 mutation, in...

BRCA2-null embryonic survival is prolonged on the BALB/c genetic background.

Bennett(L M),McAllister(K A),Blackshear(P ... Mol Carcinog 2000-09-05

...Brca1 and Brca2 genes is interdependent. The interdependence of Brca1 and Brca2 was evaluated by studying Brca2 gene exp...

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