...BRCA2 mutation carriers.,We identified 1600 cases of breast cancer and 1600 controls without breast cancer who were matc...
...BRCA2) are responsible for less than 5% of all breast cancer cases. Many studies have shown that the cancer risks associ...
...BRCA2 (4.9%), and in two index cases a deleterious change in both BRCA1 and BRCA2 was identified. Eleven deleterious cha...
...BRCA2, ATM or NBS1. Moreover, BRCA2 that plays a crucial role in homologous recombination is one of FA proteins. Collect...
...BRCA2 function downstream of this step. The FA proteins typically lack functional domains, except for FANCJ/BRIP1 and FA...
...BRCA2 mutations. Recent studies show improved specificity of MRI, likely related to advances in technique and the develo...
...BRCA2, ESR1, XRCC1, XRCC2, XRCC3, NBN, RAD51, RAD52, LIG4, ATM, BCL2, TGFB1, MSH6, ERCC2, XPF, NR3C1, CYP1A1, CYP2C9, CY...
Germline mutations in BRCA1 and BRCA2 predispose female carriers to breast and ovarian cancer. The majority of mutations...
...BRCA2 executes its functions is not well understood. We previously described a functional homologue of BRCA2 in Caenorha...
Germline mutations of BRCA1 and BRCA2 increase the risk for breast cancer. Mutation carriers selecting breast-conservati...
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